Managing cardiovascular risk in people living with HIV in Asia – where are we now?

Jun Yong Choi, Grace Chung Yan Lui, Chia Te Liao, Chia Jui Yang

Research output: Contribution to journalReview articlepeer-review

Abstract

As the life expectancy of people living with HIV (PLWH) approaches that of the general population, the burden of comorbidities such as cardiovascular disease (CVD) is increasing. Regardless of HIV status, about 50% of CVD deaths worldwide occur in Asia, and Asian PLWH have a high prevalence of conventional CVD risk factors, such as smoking, dyslipidaemia, hypertension and insulin resistance or diabetes. As well as conventional CVD risk factors, PLWH have HIV-specific risk factors such as chronic inflammation, immune activation and endothelial damage, as well as risk factors related to antiretroviral therapy. This review describes the current knowledge on the epidemiology and risk factors of CVD in Asian PLWH and provides an Asian perspective on the recommendations for managing CVD risk in PLWH.

Original languageEnglish
Pages (from-to)111-120
Number of pages10
JournalHIV Medicine
Volume23
Issue number2
DOIs
Publication statusPublished - 2022 Feb

Bibliographical note

Funding Information:
JYC has no relevant disclosures to declare. CYGL has received research grants from Gilead, MSD, Janssen and ViiV Healthcare, and consultancy fees from Gilead, MSD, ViiV Healthcare and Sanofi Pasteur. CTL has no relevant disclosures to declare. CJY has received consultancy fees from Gilead, MSD and ViiV Healthcare, and speaker fees from Gilead, Janssen, ViiV Healthcare and AbbVie.

Publisher Copyright:
© 2021 British HIV Association.

All Science Journal Classification (ASJC) codes

  • Health Policy
  • Infectious Diseases
  • Pharmacology (medical)

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