Measurement depth enhancement in terahertz imaging of biological tissues

Seung Jae Oh, Sang Hoon Kim, Kiyoung Jeong, Yeonji Park, Yong Min Huh, Joo Hiuk Son, Jin Suck Suh

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

We demonstrate the use of a THz penetration-enhancing agent (THz-PEA) to enhance the terahertz (THz) wave penetration depth in tissues. The THz-PEA is a biocompatible material having absorption lower than that of water, and it is easily absorbed into tissues. When using glycerol as a THz-PEA, the peak value of the THz signal which was transmitted through the fresh tissue and reflected by a metal target, was almost doubled compared to that of tissue without glycerol. THz time-offlight imaging (B-scan) was used to display the sequential glycerol delivery images. Enhancement of the penetration depth was confirmed after an artificial tumor was located below fresh skin. We thus concluded that the THz-PEA technique can potentially be employed to enhance the image contrast of the abnormal lesions below the skin.

Original languageEnglish
Pages (from-to)21299-21305
Number of pages7
JournalOptics Express
Volume21
Issue number18
DOIs
Publication statusPublished - 2013 Sep 9

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All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

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