Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)

Masataka Nakanishi, Woo Dong Jang, Makoto Oba, Yuichi Yamasaki, Kazunori Kataoka

Research output: Contribution to conferencePaper

Abstract

The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.

Original languageEnglish
Pages2467-2468
Number of pages2
Publication statusPublished - 2006 Dec 1
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: 2006 Sep 202006 Sep 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period06/9/2006/9/22

Fingerprint

Kinetics
Polymers
Biomaterials
Amino acids
Amines
Esters

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Nakanishi, M., Jang, W. D., Oba, M., Yamasaki, Y., & Kataoka, K. (2006). Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA). 2467-2468. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.
Nakanishi, Masataka ; Jang, Woo Dong ; Oba, Makoto ; Yamasaki, Yuichi ; Kataoka, Kazunori. / Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA). Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.2 p.
@conference{09eac1af93a640f9903b2010cafa3ffe,
title = "Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)",
abstract = "The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.",
author = "Masataka Nakanishi and Jang, {Woo Dong} and Makoto Oba and Yuichi Yamasaki and Kazunori Kataoka",
year = "2006",
month = "12",
day = "1",
language = "English",
pages = "2467--2468",
note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

}

Nakanishi, M, Jang, WD, Oba, M, Yamasaki, Y & Kataoka, K 2006, 'Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)' Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan, 06/9/20 - 06/9/22, pp. 2467-2468.

Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA). / Nakanishi, Masataka; Jang, Woo Dong; Oba, Makoto; Yamasaki, Yuichi; Kataoka, Kazunori.

2006. 2467-2468 Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.

Research output: Contribution to conferencePaper

TY - CONF

T1 - Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)

AU - Nakanishi, Masataka

AU - Jang, Woo Dong

AU - Oba, Makoto

AU - Yamasaki, Yuichi

AU - Kataoka, Kazunori

PY - 2006/12/1

Y1 - 2006/12/1

N2 - The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.

AB - The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.

UR - http://www.scopus.com/inward/record.url?scp=33846164448&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846164448&partnerID=8YFLogxK

M3 - Paper

SP - 2467

EP - 2468

ER -

Nakanishi M, Jang WD, Oba M, Yamasaki Y, Kataoka K. Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA). 2006. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.