The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.
|Number of pages||2|
|Publication status||Published - 2006 Dec 1|
|Event||55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan|
Duration: 2006 Sep 20 → 2006 Sep 22
|Other||55th Society of Polymer Science Japan Symposium on Macromolecules|
|Period||06/9/20 → 06/9/22|
All Science Journal Classification (ASJC) codes