Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)

Masataka Nakanishi; Woo Dong Jang; Makoto Oba; Yuichi Yamasaki; Kazunori Kataoka

Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)

Masataka Nakanishi, Woo Dong Jang, Makoto Oba, Yuichi Yamasaki, Kazunori Kataoka

Department of Chemistry

Research output: Contribution to conference › Paper › peer-review

Abstract

The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.

Original language	English
Pages	2467-2468
Number of pages	2
Publication status	Published - 2006
Event	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: 2006 Sept 20 → 2006 Sept 22

Other

Other	55th Society of Polymer Science Japan Symposium on Macromolecules
Country/Territory	Japan
City	Toyama
Period	06/9/20 → 06/9/22

All Science Journal Classification (ASJC) codes

Engineering(all)

Cite this

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title = "Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)",

abstract = "The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.",

author = "Masataka Nakanishi and Jang, {Woo Dong} and Makoto Oba and Yuichi Yamasaki and Kazunori Kataoka",

year = "2006",

language = "English",

pages = "2467--2468",

note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

}

TY - CONF

T1 - Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)

AU - Nakanishi, Masataka

AU - Jang, Woo Dong

AU - Oba, Makoto

AU - Yamasaki, Yuichi

AU - Kataoka, Kazunori

PY - 2006

Y1 - 2006

N2 - The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.

AB - The amino acid-based polymers have been attracting remarkable attention owing to their wide potential utilities for biomaterials. Recently, we found that the flanking benzyl ester groups of poly(β-benzyl-L-aspartate) (PBLA) can undergo a quantitative aminolysis reaction with various primary amine compounds, thus allowing the preparation of a variety of polyaspartamides with different functionality from a single platform polymer. The mechanism and kinetics of the quantitative aminolysis of PBLA has been investigated, focusing on racemization and α to β transition from the standpoint of higher-ordered structure of polymer strands.

UR - http://www.scopus.com/inward/record.url?scp=33846164448&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846164448&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33846164448

SP - 2467

EP - 2468

T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -

Mechanism and kinetics of quantitative aminolysis reaction of poly(β-benzyl-L-aspartate)(PBLA)

Abstract

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All Science Journal Classification (ASJC) codes

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