TY - JOUR
T1 - Membranous lipodystrophy
T2 - Primary idiopathic type
AU - Chun, Soo Il
AU - Ahn, Sung Ku
AU - Kim, Soo Chan
PY - 1991
Y1 - 1991
N2 - A 20-year-old woman had a pea-sized, tender subcutaneous nodule on the leg. Histopatho-logically, the panniculus showed multiple microcysts lined by membranes and light brown granules in the histiocytes. Histochemical studies of the membranes of the microcysts and the granules in the histiocytes indicated that they were composed of ceroid. Electron microscopy revealed that the membrane of the microcyst was composed of electron-dense areas of a regular 18.6 nm lamellar array and reticulated vacuolated areas suggestive of degenerating fat cells of unknown origin. Membranous lipodystrophy has been associated with many local and systemic diseases, but it may be idiopathic, as in our patient.
AB - A 20-year-old woman had a pea-sized, tender subcutaneous nodule on the leg. Histopatho-logically, the panniculus showed multiple microcysts lined by membranes and light brown granules in the histiocytes. Histochemical studies of the membranes of the microcysts and the granules in the histiocytes indicated that they were composed of ceroid. Electron microscopy revealed that the membrane of the microcyst was composed of electron-dense areas of a regular 18.6 nm lamellar array and reticulated vacuolated areas suggestive of degenerating fat cells of unknown origin. Membranous lipodystrophy has been associated with many local and systemic diseases, but it may be idiopathic, as in our patient.
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U2 - 10.1016/0190-9622(91)70129-P
DO - 10.1016/0190-9622(91)70129-P
M3 - Article
C2 - 2050851
AN - SCOPUS:0025831596
SN - 0190-9622
VL - 24
SP - 844
EP - 847
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 5
ER -