MEMS based hybrid blood cell sorter for applications in lab-on-a-chip

Hye Kyoung Seo, Yong Ho Kim, Hyun Ok Kim, Yong Jun Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, a hybrid chip was demonstrated for classifying biological particles according to their size and magnetic property. The proposed hybrid cell sorter (HCS) was realized using a hydrodynamic particle sorter, a micromachined virtual impactor. The HCS is fabricated through simple silicon surface micromachining. For performance test, Jurkat cells and human monocytes were classified. In experimental results, the sorting efficiencies of Jurkat cells and human red blood cells(RBCs) and white blood cells (WBCs) were enhanced by induced magnetic flux density.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1904-1906
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - 2009 Jan 1
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 2009 Nov 12009 Nov 5

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period09/11/109/11/5

Fingerprint

Lab-on-a-chip
MEMS
Blood
Cells
Surface micromachining
Silicon
Magnetic flux
Sorting
Magnetic properties
Hydrodynamics

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Seo, H. K., Kim, Y. H., Kim, H. O., & Kim, Y. J. (2009). MEMS based hybrid blood cell sorter for applications in lab-on-a-chip. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1904-1906). (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.
Seo, Hye Kyoung ; Kim, Yong Ho ; Kim, Hyun Ok ; Kim, Yong Jun. / MEMS based hybrid blood cell sorter for applications in lab-on-a-chip. Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2009. pp. 1904-1906 (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences).
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abstract = "In this paper, a hybrid chip was demonstrated for classifying biological particles according to their size and magnetic property. The proposed hybrid cell sorter (HCS) was realized using a hydrodynamic particle sorter, a micromachined virtual impactor. The HCS is fabricated through simple silicon surface micromachining. For performance test, Jurkat cells and human monocytes were classified. In experimental results, the sorting efficiencies of Jurkat cells and human red blood cells(RBCs) and white blood cells (WBCs) were enhanced by induced magnetic flux density.",
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Seo, HK, Kim, YH, Kim, HO & Kim, YJ 2009, MEMS based hybrid blood cell sorter for applications in lab-on-a-chip. in Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 1904-1906, 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009, Jeju, Korea, Republic of, 09/11/1.

MEMS based hybrid blood cell sorter for applications in lab-on-a-chip. / Seo, Hye Kyoung; Kim, Yong Ho; Kim, Hyun Ok; Kim, Yong Jun.

Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2009. p. 1904-1906 (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Seo HK, Kim YH, Kim HO, Kim YJ. MEMS based hybrid blood cell sorter for applications in lab-on-a-chip. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2009. p. 1904-1906. (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences).