Abstract
Different techniques and methods of electrochromatography on "lab on a chip" devices are reviewed. Described approaches include open-channel microchip electrochromatography relying on C8, C18 and novel gold nanoparticle (GNP) coating of microchannel wall; packed-channel microchip electrochromatography with new ways of automated loading and unloading of conventional octadecylsilica beads; monolith-based microchip electrochromatography with tailored casting of stationary phase at the specific places of microfluidic network and novel photolitographically fabricated collocated monolithic structures. Specific issues related to the microchip electrochromatography, i.e. importance of high aspect ratio of the microchannels in the open-channel electrochromatography or approaches eliminating the wall effect in the monolith-based electrochromatography, are discussed. Various applications for environmental, pharmacological, genomic and proteomic analysis are described. The operation parameters of reviewed microsystems are summarized in easy-to-read tables.
| Original language | English |
|---|---|
| Pages (from-to) | 1048-1062 |
| Number of pages | 15 |
| Journal | Talanta |
| Volume | 66 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2005 May 15 |
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All Science Journal Classification (ASJC) codes
- Analytical Chemistry
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Microchip-based electrochromatography : Designs and applications. / Pumera, Martin.
In: Talanta, Vol. 66, No. 4, 15.05.2005, p. 1048-1062.Research output: Contribution to journal › Article
TY - JOUR
T1 - Microchip-based electrochromatography
T2 - Designs and applications
AU - Pumera, Martin
PY - 2005/5/15
Y1 - 2005/5/15
N2 - Different techniques and methods of electrochromatography on "lab on a chip" devices are reviewed. Described approaches include open-channel microchip electrochromatography relying on C8, C18 and novel gold nanoparticle (GNP) coating of microchannel wall; packed-channel microchip electrochromatography with new ways of automated loading and unloading of conventional octadecylsilica beads; monolith-based microchip electrochromatography with tailored casting of stationary phase at the specific places of microfluidic network and novel photolitographically fabricated collocated monolithic structures. Specific issues related to the microchip electrochromatography, i.e. importance of high aspect ratio of the microchannels in the open-channel electrochromatography or approaches eliminating the wall effect in the monolith-based electrochromatography, are discussed. Various applications for environmental, pharmacological, genomic and proteomic analysis are described. The operation parameters of reviewed microsystems are summarized in easy-to-read tables.
AB - Different techniques and methods of electrochromatography on "lab on a chip" devices are reviewed. Described approaches include open-channel microchip electrochromatography relying on C8, C18 and novel gold nanoparticle (GNP) coating of microchannel wall; packed-channel microchip electrochromatography with new ways of automated loading and unloading of conventional octadecylsilica beads; monolith-based microchip electrochromatography with tailored casting of stationary phase at the specific places of microfluidic network and novel photolitographically fabricated collocated monolithic structures. Specific issues related to the microchip electrochromatography, i.e. importance of high aspect ratio of the microchannels in the open-channel electrochromatography or approaches eliminating the wall effect in the monolith-based electrochromatography, are discussed. Various applications for environmental, pharmacological, genomic and proteomic analysis are described. The operation parameters of reviewed microsystems are summarized in easy-to-read tables.
UR - http://www.scopus.com/inward/record.url?scp=18844367723&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=18844367723&partnerID=8YFLogxK
U2 - 10.1016/j.talanta.2005.01.006
DO - 10.1016/j.talanta.2005.01.006
M3 - Article
C2 - 18970090
AN - SCOPUS:18844367723
VL - 66
SP - 1048
EP - 1062
JO - Talanta
JF - Talanta
SN - 0039-9140
IS - 4
ER -