Microchip-based electrochromatography: Designs and applications

Martin Pumera

doi:10.1016/j.talanta.2005.01.006

Microchip-based electrochromatography: Designs and applications

Martin Pumera

Department of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

87 Citations (Scopus)

Abstract

Different techniques and methods of electrochromatography on "lab on a chip" devices are reviewed. Described approaches include open-channel microchip electrochromatography relying on C₈, C₁₈ and novel gold nanoparticle (GNP) coating of microchannel wall; packed-channel microchip electrochromatography with new ways of automated loading and unloading of conventional octadecylsilica beads; monolith-based microchip electrochromatography with tailored casting of stationary phase at the specific places of microfluidic network and novel photolitographically fabricated collocated monolithic structures. Specific issues related to the microchip electrochromatography, i.e. importance of high aspect ratio of the microchannels in the open-channel electrochromatography or approaches eliminating the wall effect in the monolith-based electrochromatography, are discussed. Various applications for environmental, pharmacological, genomic and proteomic analysis are described. The operation parameters of reviewed microsystems are summarized in easy-to-read tables.

Original language	English
Pages (from-to)	1048-1062
Number of pages	15
Journal	Talanta
Volume	66
Issue number	4
DOIs	https://doi.org/10.1016/j.talanta.2005.01.006
Publication status	Published - 2005 May 15

Bibliographical note

Funding Information:
This work was supported by NATO Science Program.

All Science Journal Classification (ASJC) codes

Analytical Chemistry

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10.1016/j.talanta.2005.01.006

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Microchip-based electrochromatography: Designs and applications

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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