@inproceedings{df28979efb6847f9a447d76e0edabc4f,
title = "Microfluidic cell stimulator using bead impact",
abstract = "Recently many researchers are focused on cell stimulation regarding observation of cells to specific stimulation factors. We introduce new mechanical stimulation method using micro beads without any chemical reagents. CPAE (calf pulmonary artery endothelial cell) were cultured in PDMS (polydimethylsiloxane) microfluidic device. After starvation process, sterilized 10|im glass beads were rolled by only gravitational force for 10 minute. To find optimal stimulation time, 16 devices were made by PDMS and each device was slanted every hour. Results show that cell exposed under micro bead stimulation perform at a higher growth rate than normal conditions and 1 hour stimulation time represents more effective than other stimulation times. This new cell stimulation method will be able to help make artificial organ such as blood vessels in the future.",
author = "Kim, {Young Hun} and Kim, {Tae Jin} and Kim, {Hyung Joon} and Park, {Min Suk} and Jung, {Hyo I.}",
year = "2009",
language = "English",
isbn = "9789898111647",
series = "BIODEVICES 2009 - Proceedings of the 2nd International Conference on Biomedical Electronics and Devices",
pages = "426--429",
booktitle = "BIODEVICES 2009 - Proceedings of the 2nd International Conference on Biomedical Electronics and Devices",
note = "2nd International Conference on Biomedical Electronics and Devices, BIODEVICES 2009 ; Conference date: 14-01-2009 Through 17-01-2009",
}