Microfluidic components and bio-reactors for miniaturized bio-chip applications

Kwang Seok Yun, Euisik Yoon

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

In this paper miniaturized disposable micro/nanofluidic components applicable to bio chip, chemical analyzer and biomedical monitoring system, such as blood analysis, micro dosing system and cell experiment, etc are reported. This system includes various microfluidic components including a micropump, micromixer, DNA purification chip and single-cell assay chip. For low voltage and low power operation, a surface tension-driven micropump is presented, as well as a micromixer, which was implemented using MEMS technology, for efficient liquid mixing is also introduced. As bio-reactors, DNA purification and single-cell assay devices, for the extraction of pure DNA from liquid mixture or blood and for cellular engineering or high-throughput screening, respectively, are presented.

Original languageEnglish
Pages (from-to)86-92
Number of pages7
JournalBiotechnology and Bioprocess Engineering
Volume9
Issue number2
DOIs
Publication statusPublished - 2004 Dec 1

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Microfluidics
DNA
Purification
Assays
Blood
Micro-Electrical-Mechanical Systems
Nanofluidics
Cell Engineering
Surface Tension
Liquids
Oligonucleotide Array Sequence Analysis
MEMS
Surface tension
Screening
Throughput
Technology
Equipment and Supplies
Monitoring
Electric potential
Experiments

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology
  • Biomedical Engineering

Cite this

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Microfluidic components and bio-reactors for miniaturized bio-chip applications. / Yun, Kwang Seok; Yoon, Euisik.

In: Biotechnology and Bioprocess Engineering, Vol. 9, No. 2, 01.12.2004, p. 86-92.

Research output: Contribution to journalArticle

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