MKEM: A multi-level knowledge emergence model for mining undiscovered public knowledge

Ali Zeeshan Ijaz, Min Song, Doheon Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Since Swanson proposed the Undiscovered Public Knowledge (UPK) model, there have been many approaches to uncover UPK by mining the biomedical literature. These earlier works, however, required substantial manual intervention to reduce the number of possible connections and are mainly applied to disease-effect relation. With the advancement in biomedical science, it has become imperative to extract and combine information from multiple disjoint researches, studies and articles to infer new hypothesesand expand knowledge. In this paper, we propose MKEM, a Multi-level Knowledge Emergence Model, to discover implicit relationships using Natural Language Processing techniques such as Link Grammar and Ontologies such as Unified Medical Language System (UMLS) MetaMap. The contribution of MKEM is as follows: First, we propose a flexible knowledge emergence model to extract implicit relationships across different levels such as molecular level for gene and protein and Phenomic level for disease and treatment. Second, we employ MetaMap for tagging biological concepts. Third, we provide an empirical and systematic approach to discover novel relationships. Our experiments show that MKEM is a powerful tool to discover hidden relationships residing in extracted entities that were represented by our Substance-Effect-Process-Disease-Body Part (SEPDB) model.

Original languageEnglish
Title of host publication3rd ACM International Workshop on Data and Text Mining in Bioinformatics, DTMBIO'09, Co-located with the 18th ACM International Conference on Information and Knowledge Management, CIKM 2009
Pages51-58
Number of pages8
DOIs
Publication statusPublished - 2009 Dec 1
Event3rd ACM International Workshop on Data and Text Mining in Bioinformatics, DTMBIO'09, Co-located with the 18th ACM International Conference on Information and Knowledge Management, CIKM 2009 - Hong Kong, China
Duration: 2009 Nov 22009 Nov 6

Publication series

NameInternational Conference on Information and Knowledge Management, Proceedings

Other

Other3rd ACM International Workshop on Data and Text Mining in Bioinformatics, DTMBIO'09, Co-located with the 18th ACM International Conference on Information and Knowledge Management, CIKM 2009
CountryChina
CityHong Kong
Period09/11/209/11/6

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All Science Journal Classification (ASJC) codes

  • Decision Sciences(all)
  • Business, Management and Accounting(all)

Cite this

Ijaz, A. Z., Song, M., & Lee, D. (2009). MKEM: A multi-level knowledge emergence model for mining undiscovered public knowledge. In 3rd ACM International Workshop on Data and Text Mining in Bioinformatics, DTMBIO'09, Co-located with the 18th ACM International Conference on Information and Knowledge Management, CIKM 2009 (pp. 51-58). (International Conference on Information and Knowledge Management, Proceedings). https://doi.org/10.1145/1651318.1651329