MnPS3 shows anticancer behaviour towards lung cancer cells

Naziah Mohamad Latiff, Nur Farhanah Rosli, Carmen C. Mayorga-Martinez, Katerina Szokolava, Zdenek Sofer, Adrian C. Fisher, Martin Pumera

Research output: Contribution to journalArticle

Abstract

Here, we report the anticancer behaviour of MnPS3 towards lung cancer A549 cells where approximately 50% of the cells remain viable upon a low dosage of MnPS3 treatment. We found that MnPS3 triggers A549 cells to generate reactive oxygen species and undergo apoptosis leading to cell death. These findings serve as a platform for introducing MnPS3 in biomedical applications.

Original languageEnglish
Article number100134
JournalFlatChem
Volume18
DOIs
Publication statusPublished - 2019 Nov

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Cell death
Reactive Oxygen Species
Cells
Apoptosis
Oxygen

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Surfaces, Coatings and Films
  • Materials Chemistry

Cite this

Mohamad Latiff, N., Rosli, N. F., Mayorga-Martinez, C. C., Szokolava, K., Sofer, Z., Fisher, A. C., & Pumera, M. (2019). MnPS3 shows anticancer behaviour towards lung cancer cells. FlatChem, 18, [100134]. https://doi.org/10.1016/j.flatc.2019.100134
Mohamad Latiff, Naziah ; Rosli, Nur Farhanah ; Mayorga-Martinez, Carmen C. ; Szokolava, Katerina ; Sofer, Zdenek ; Fisher, Adrian C. ; Pumera, Martin. / MnPS3 shows anticancer behaviour towards lung cancer cells. In: FlatChem. 2019 ; Vol. 18.
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Mohamad Latiff, N, Rosli, NF, Mayorga-Martinez, CC, Szokolava, K, Sofer, Z, Fisher, AC & Pumera, M 2019, 'MnPS3 shows anticancer behaviour towards lung cancer cells', FlatChem, vol. 18, 100134. https://doi.org/10.1016/j.flatc.2019.100134

MnPS3 shows anticancer behaviour towards lung cancer cells. / Mohamad Latiff, Naziah; Rosli, Nur Farhanah; Mayorga-Martinez, Carmen C.; Szokolava, Katerina; Sofer, Zdenek; Fisher, Adrian C.; Pumera, Martin.

In: FlatChem, Vol. 18, 100134, 11.2019.

Research output: Contribution to journalArticle

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Mohamad Latiff N, Rosli NF, Mayorga-Martinez CC, Szokolava K, Sofer Z, Fisher AC et al. MnPS3 shows anticancer behaviour towards lung cancer cells. FlatChem. 2019 Nov;18. 100134. https://doi.org/10.1016/j.flatc.2019.100134