Molecular cloning and anti-fungal effect of endo-β-1,3-glucanase from Thermotoga maritima

Chang Bin Woo, Hae Na Kang, Soo Bok Lee

Research output: Contribution to journalEditorial

4 Citations (Scopus)


A gene encoding an endo-β-1,3-glucanase from Thermotoga maritima MSB8 (TmβG) was cloned and expressed in Escherichia coli. The purified enzyme produced various β-1,3-glucooligosaccharides from soluble laminarin, and mainly β-1,3-glucooligosaccharides smaller than laminaritetrose from insoluble curdlan. The optimum pH and temperature of the enzyme were 5.0 and 80°C, respectively. TmβG inhibited the growth of Candida albicans, which indicates that the enzyme could potentially be used as an anti-fungal agent to control invasive infections.

Original languageEnglish
Pages (from-to)1243-1246
Number of pages4
JournalFood Science and Biotechnology
Issue number4
Publication statusPublished - 2014 Aug


All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology

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