Molecular Pathogenesis of Corneal Dystrophies

Schnyder Dystrophy and Granular Corneal Dystrophy type 2

Eungkweon Kim, Hun Lee, Seung Il Choi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The International Committee for Classification of Corneal Dystrophies (IC3D) provides updated data to ophthalmologists by incorporating traditional definitions of corneal dystrophies with new genetic, clinical, and pathologic information. Recent advances in the genetics of corneal dystrophies facilitate more precise classifications and elucidate each classification's molecular mechanisms. Unfortunately, the molecular mechanisms and underlying pathogenic mechanisms have remained obscure, with the exception of Schnyder corneal dystrophy (CD), granular CD type 2 (GCD2), and Fuch's endothelial CD. Here, we review the pathogenesis of Schnyder CD and GCD2.

Original languageEnglish
Title of host publicationMolecular Biology of Eye Disease, 2015
EditorsJohn M. Nickerson, J. Fielding Hejtmancik
PublisherElsevier B.V.
Pages99-115
Number of pages17
ISBN (Print)9780128010594
DOIs
Publication statusPublished - 2015 Jan 1

Publication series

NameProgress in Molecular Biology and Translational Science
Volume134
ISSN (Print)1877-1173
ISSN (Electronic)1878-0814

Fingerprint

Fuchs' Endothelial Dystrophy
Corneal Dystrophy, Crystalline, of Schnyder
Corneal dystrophy Avellino type
Ophthalmologists
Groenouw type I corneal dystrophy

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Molecular Biology

Cite this

Kim, E., Lee, H., & Choi, S. I. (2015). Molecular Pathogenesis of Corneal Dystrophies: Schnyder Dystrophy and Granular Corneal Dystrophy type 2. In J. M. Nickerson, & J. F. Hejtmancik (Eds.), Molecular Biology of Eye Disease, 2015 (pp. 99-115). (Progress in Molecular Biology and Translational Science; Vol. 134). Elsevier B.V.. https://doi.org/10.1016/bs.pmbts.2015.05.003
Kim, Eungkweon ; Lee, Hun ; Choi, Seung Il. / Molecular Pathogenesis of Corneal Dystrophies : Schnyder Dystrophy and Granular Corneal Dystrophy type 2. Molecular Biology of Eye Disease, 2015. editor / John M. Nickerson ; J. Fielding Hejtmancik. Elsevier B.V., 2015. pp. 99-115 (Progress in Molecular Biology and Translational Science).
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Kim, E, Lee, H & Choi, SI 2015, Molecular Pathogenesis of Corneal Dystrophies: Schnyder Dystrophy and Granular Corneal Dystrophy type 2. in JM Nickerson & JF Hejtmancik (eds), Molecular Biology of Eye Disease, 2015. Progress in Molecular Biology and Translational Science, vol. 134, Elsevier B.V., pp. 99-115. https://doi.org/10.1016/bs.pmbts.2015.05.003

Molecular Pathogenesis of Corneal Dystrophies : Schnyder Dystrophy and Granular Corneal Dystrophy type 2. / Kim, Eungkweon; Lee, Hun; Choi, Seung Il.

Molecular Biology of Eye Disease, 2015. ed. / John M. Nickerson; J. Fielding Hejtmancik. Elsevier B.V., 2015. p. 99-115 (Progress in Molecular Biology and Translational Science; Vol. 134).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Kim E, Lee H, Choi SI. Molecular Pathogenesis of Corneal Dystrophies: Schnyder Dystrophy and Granular Corneal Dystrophy type 2. In Nickerson JM, Hejtmancik JF, editors, Molecular Biology of Eye Disease, 2015. Elsevier B.V. 2015. p. 99-115. (Progress in Molecular Biology and Translational Science). https://doi.org/10.1016/bs.pmbts.2015.05.003