Molecular targets of exercise mimetics and their natural activators

Young Jin Jang; Sanguine Byun

doi:10.5483/BMBRep.2021.54.12.151

Molecular targets of exercise mimetics and their natural activators

Young Jin Jang, Sanguine Byun

Division of Life Sciences

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Physical exercise can be effective in preventing or ameliorating various diseases, including diabetes, cardiovascular diseases,neurodegenerative diseases, and cancer. However, not everyonemay be able to participate in exercise due to illnesses, age-relatedfrailty, or difficulty in long-term behavior change. Analternative option is to utilize pharmacological interventions thatmimic the positive effects of exercise training. Recent studieshave identified signaling pathways associated with the benefitsof physical activity and discovered exercise mimetics that canpartially simulate the systemic impact of exercise. This reviewdescribes the molecular targets for exercise mimetics and theireffect on skeletal muscle and other tissues.

Original language	English
Pages (from-to)	581-591
Number of pages	11
Journal	BMB reports
Volume	54
Issue number	12
DOIs	https://doi.org/10.5483/BMBRep.2021.54.12.151
Publication status	Published - 2021

Bibliographical note

Funding Information:
This research was supported by a research grant from Seoul Women’s University (2020-0452) and the Yonsei University Research Fund of 2020-22-0073.

Publisher Copyright:
© 2021. by the The Korean Society for Biochemistry and Molecular Biology

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.5483/BMBRep.2021.54.12.151

Cite this

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Molecular targets of exercise mimetics and their natural activators

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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