Monotherapy in patients with type 2 diabetes mellitus

Sang Youl Rhee, Hyun Jin Kim, Seung Hyun Ko, Kyu Yeon Hur, Nan Hee Kim, Min Kyong Moon, Seok O. Park, byungwan lee, Kyung Mook Choi, Jin Hwa Kim

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

In order to improve the quality of life and to prevent chronic complications related to diabetes mellitus, intensive lifestyle modification and proper medication are needed from the early stage of diagnosis of type 2 diabetes mellitus (T2DM). When using the first medication for diabetic patients, the appropriate treatment should be selected considering the clinical characteristics of the patient, efficacy of the drug, side effects, and cost. In general, the use of metformin as the first treatment for oral hypoglycemic monotherapy is recommended because of its excellent blood glucose-lowering effect, relatively low side effects, long-term proven safety, low risk of hypoglycemia, and low weight gain. If metformin is difficult to use as a first-line treatment, other appropriate medications should be selected in view of the clinical situation. If the goal of achieving glycemic control is not achieved by monotherapy, a combination therapy with different mechanisms of action should be initiated promptly.

Original languageEnglish
Pages (from-to)959-966
Number of pages8
JournalKorean Journal of Internal Medicine
Volume32
Issue number6
DOIs
Publication statusPublished - 2017 Nov 1

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Type 2 Diabetes Mellitus
Metformin
Therapeutics
Drug-Related Side Effects and Adverse Reactions
Hypoglycemia
Hypoglycemic Agents
Weight Gain
Blood Glucose
Life Style
Early Diagnosis
Diabetes Mellitus
Quality of Life
Safety
Costs and Cost Analysis

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Rhee, S. Y., Kim, H. J., Ko, S. H., Hur, K. Y., Kim, N. H., Moon, M. K., ... Kim, J. H. (2017). Monotherapy in patients with type 2 diabetes mellitus. Korean Journal of Internal Medicine, 32(6), 959-966. https://doi.org/10.3904/kjim.2017.312
Rhee, Sang Youl ; Kim, Hyun Jin ; Ko, Seung Hyun ; Hur, Kyu Yeon ; Kim, Nan Hee ; Moon, Min Kyong ; Park, Seok O. ; lee, byungwan ; Choi, Kyung Mook ; Kim, Jin Hwa. / Monotherapy in patients with type 2 diabetes mellitus. In: Korean Journal of Internal Medicine. 2017 ; Vol. 32, No. 6. pp. 959-966.
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Rhee, SY, Kim, HJ, Ko, SH, Hur, KY, Kim, NH, Moon, MK, Park, SO, lee, B, Choi, KM & Kim, JH 2017, 'Monotherapy in patients with type 2 diabetes mellitus', Korean Journal of Internal Medicine, vol. 32, no. 6, pp. 959-966. https://doi.org/10.3904/kjim.2017.312

Monotherapy in patients with type 2 diabetes mellitus. / Rhee, Sang Youl; Kim, Hyun Jin; Ko, Seung Hyun; Hur, Kyu Yeon; Kim, Nan Hee; Moon, Min Kyong; Park, Seok O.; lee, byungwan; Choi, Kyung Mook; Kim, Jin Hwa.

In: Korean Journal of Internal Medicine, Vol. 32, No. 6, 01.11.2017, p. 959-966.

Research output: Contribution to journalReview article

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AU - Rhee, Sang Youl

AU - Kim, Hyun Jin

AU - Ko, Seung Hyun

AU - Hur, Kyu Yeon

AU - Kim, Nan Hee

AU - Moon, Min Kyong

AU - Park, Seok O.

AU - lee, byungwan

AU - Choi, Kyung Mook

AU - Kim, Jin Hwa

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Rhee SY, Kim HJ, Ko SH, Hur KY, Kim NH, Moon MK et al. Monotherapy in patients with type 2 diabetes mellitus. Korean Journal of Internal Medicine. 2017 Nov 1;32(6):959-966. https://doi.org/10.3904/kjim.2017.312