MR-DWI-positive lesions and symptomatic ischemic complications after coiling of unruptured intracranial aneurysms

Dong Hun Kang, Byungmoon Kim, Dong Joon Kim, Sang Hyun Suh, Dong Ik Kim, Yong Sun Kim, Seung Kon Huh, Jaechan Park, Jae Whan Lee, Yong Bae Kim

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background and Purpose-The aims of this study are to evaluate the risk factors for symptomatic ischemic complication (symptomatic ischemic complication [SIC], transient ischemic attack, or stroke) and microembolisms detected as MR diffusion-weighted imaging (MR-DWI)-positive (DWI(+)) lesions, and the relationship between DWI(+) and SIC after coiling of unruptured intracranial aneurysm. Methods-Between March 2009 and November 2011, 382 unruptured intracranial aneurysms in 343 patients underwent both coiling and posttreatment MR-DWI. The incidence of and risk factors for SIC and DWI(+), and the relationship between DWI(+) and SIC were retrospectively analyzed. Results-The incidence of SIC was 4.1%. The incidence of DWI(+) was 54.5%. The number of DWI(+) lesions was significantly larger in the SIC group, than in the asymptomatic one (12.1±10.4 versus 5.0±8.7, P<0.00). The cutoff value of DWI(+) for predicting SIC was ≥6 (sensitivity 85.7%, specificity 70.7%). The patients with DWI(+) ≥6 was 28.6%. Of the patients with SIC, the patients with DWI(+) ≥6 was 78.6%. Patients aged≥65 years had a trend for SIC, and it was the only independent risk factor for DWI(+) ≥cutoff (n=6; 95%CI, 1.167-3.083). Conclusions-The number of DWI(+) lesions was significantly larger in the SIC group than in the asymptomatic one after coiling of unruptured intracranial aneurysm. Patients aged≥65 had a trend for SIC, and it was the only independent risk factor for the number of DWI(+) ≥cutoff value (n=6) for predicting SIC.

Original languageEnglish
Pages (from-to)789-791
Number of pages3
JournalStroke
Volume44
Issue number3
DOIs
Publication statusPublished - 2013 Mar 1

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Intracranial Aneurysm
Incidence
Transient Ischemic Attack
Stroke
Sensitivity and Specificity

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialised Nursing

Cite this

Kang, Dong Hun ; Kim, Byungmoon ; Kim, Dong Joon ; Suh, Sang Hyun ; Kim, Dong Ik ; Kim, Yong Sun ; Huh, Seung Kon ; Park, Jaechan ; Lee, Jae Whan ; Kim, Yong Bae. / MR-DWI-positive lesions and symptomatic ischemic complications after coiling of unruptured intracranial aneurysms. In: Stroke. 2013 ; Vol. 44, No. 3. pp. 789-791.
@article{3172fd6cefa748d1bebfb13fc15913eb,
title = "MR-DWI-positive lesions and symptomatic ischemic complications after coiling of unruptured intracranial aneurysms",
abstract = "Background and Purpose-The aims of this study are to evaluate the risk factors for symptomatic ischemic complication (symptomatic ischemic complication [SIC], transient ischemic attack, or stroke) and microembolisms detected as MR diffusion-weighted imaging (MR-DWI)-positive (DWI(+)) lesions, and the relationship between DWI(+) and SIC after coiling of unruptured intracranial aneurysm. Methods-Between March 2009 and November 2011, 382 unruptured intracranial aneurysms in 343 patients underwent both coiling and posttreatment MR-DWI. The incidence of and risk factors for SIC and DWI(+), and the relationship between DWI(+) and SIC were retrospectively analyzed. Results-The incidence of SIC was 4.1{\%}. The incidence of DWI(+) was 54.5{\%}. The number of DWI(+) lesions was significantly larger in the SIC group, than in the asymptomatic one (12.1±10.4 versus 5.0±8.7, P<0.00). The cutoff value of DWI(+) for predicting SIC was ≥6 (sensitivity 85.7{\%}, specificity 70.7{\%}). The patients with DWI(+) ≥6 was 28.6{\%}. Of the patients with SIC, the patients with DWI(+) ≥6 was 78.6{\%}. Patients aged≥65 years had a trend for SIC, and it was the only independent risk factor for DWI(+) ≥cutoff (n=6; 95{\%}CI, 1.167-3.083). Conclusions-The number of DWI(+) lesions was significantly larger in the SIC group than in the asymptomatic one after coiling of unruptured intracranial aneurysm. Patients aged≥65 had a trend for SIC, and it was the only independent risk factor for the number of DWI(+) ≥cutoff value (n=6) for predicting SIC.",
author = "Kang, {Dong Hun} and Byungmoon Kim and Kim, {Dong Joon} and Suh, {Sang Hyun} and Kim, {Dong Ik} and Kim, {Yong Sun} and Huh, {Seung Kon} and Jaechan Park and Lee, {Jae Whan} and Kim, {Yong Bae}",
year = "2013",
month = "3",
day = "1",
doi = "10.1161/STROKEAHA.112.669853",
language = "English",
volume = "44",
pages = "789--791",
journal = "Stroke",
issn = "0039-2499",
publisher = "Lippincott Williams and Wilkins",
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Kang, DH, Kim, B, Kim, DJ, Suh, SH, Kim, DI, Kim, YS, Huh, SK, Park, J, Lee, JW & Kim, YB 2013, 'MR-DWI-positive lesions and symptomatic ischemic complications after coiling of unruptured intracranial aneurysms', Stroke, vol. 44, no. 3, pp. 789-791. https://doi.org/10.1161/STROKEAHA.112.669853

MR-DWI-positive lesions and symptomatic ischemic complications after coiling of unruptured intracranial aneurysms. / Kang, Dong Hun; Kim, Byungmoon; Kim, Dong Joon; Suh, Sang Hyun; Kim, Dong Ik; Kim, Yong Sun; Huh, Seung Kon; Park, Jaechan; Lee, Jae Whan; Kim, Yong Bae.

In: Stroke, Vol. 44, No. 3, 01.03.2013, p. 789-791.

Research output: Contribution to journalArticle

TY - JOUR

T1 - MR-DWI-positive lesions and symptomatic ischemic complications after coiling of unruptured intracranial aneurysms

AU - Kang, Dong Hun

AU - Kim, Byungmoon

AU - Kim, Dong Joon

AU - Suh, Sang Hyun

AU - Kim, Dong Ik

AU - Kim, Yong Sun

AU - Huh, Seung Kon

AU - Park, Jaechan

AU - Lee, Jae Whan

AU - Kim, Yong Bae

PY - 2013/3/1

Y1 - 2013/3/1

N2 - Background and Purpose-The aims of this study are to evaluate the risk factors for symptomatic ischemic complication (symptomatic ischemic complication [SIC], transient ischemic attack, or stroke) and microembolisms detected as MR diffusion-weighted imaging (MR-DWI)-positive (DWI(+)) lesions, and the relationship between DWI(+) and SIC after coiling of unruptured intracranial aneurysm. Methods-Between March 2009 and November 2011, 382 unruptured intracranial aneurysms in 343 patients underwent both coiling and posttreatment MR-DWI. The incidence of and risk factors for SIC and DWI(+), and the relationship between DWI(+) and SIC were retrospectively analyzed. Results-The incidence of SIC was 4.1%. The incidence of DWI(+) was 54.5%. The number of DWI(+) lesions was significantly larger in the SIC group, than in the asymptomatic one (12.1±10.4 versus 5.0±8.7, P<0.00). The cutoff value of DWI(+) for predicting SIC was ≥6 (sensitivity 85.7%, specificity 70.7%). The patients with DWI(+) ≥6 was 28.6%. Of the patients with SIC, the patients with DWI(+) ≥6 was 78.6%. Patients aged≥65 years had a trend for SIC, and it was the only independent risk factor for DWI(+) ≥cutoff (n=6; 95%CI, 1.167-3.083). Conclusions-The number of DWI(+) lesions was significantly larger in the SIC group than in the asymptomatic one after coiling of unruptured intracranial aneurysm. Patients aged≥65 had a trend for SIC, and it was the only independent risk factor for the number of DWI(+) ≥cutoff value (n=6) for predicting SIC.

AB - Background and Purpose-The aims of this study are to evaluate the risk factors for symptomatic ischemic complication (symptomatic ischemic complication [SIC], transient ischemic attack, or stroke) and microembolisms detected as MR diffusion-weighted imaging (MR-DWI)-positive (DWI(+)) lesions, and the relationship between DWI(+) and SIC after coiling of unruptured intracranial aneurysm. Methods-Between March 2009 and November 2011, 382 unruptured intracranial aneurysms in 343 patients underwent both coiling and posttreatment MR-DWI. The incidence of and risk factors for SIC and DWI(+), and the relationship between DWI(+) and SIC were retrospectively analyzed. Results-The incidence of SIC was 4.1%. The incidence of DWI(+) was 54.5%. The number of DWI(+) lesions was significantly larger in the SIC group, than in the asymptomatic one (12.1±10.4 versus 5.0±8.7, P<0.00). The cutoff value of DWI(+) for predicting SIC was ≥6 (sensitivity 85.7%, specificity 70.7%). The patients with DWI(+) ≥6 was 28.6%. Of the patients with SIC, the patients with DWI(+) ≥6 was 78.6%. Patients aged≥65 years had a trend for SIC, and it was the only independent risk factor for DWI(+) ≥cutoff (n=6; 95%CI, 1.167-3.083). Conclusions-The number of DWI(+) lesions was significantly larger in the SIC group than in the asymptomatic one after coiling of unruptured intracranial aneurysm. Patients aged≥65 had a trend for SIC, and it was the only independent risk factor for the number of DWI(+) ≥cutoff value (n=6) for predicting SIC.

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U2 - 10.1161/STROKEAHA.112.669853

DO - 10.1161/STROKEAHA.112.669853

M3 - Article

C2 - 23204052

AN - SCOPUS:84876285258

VL - 44

SP - 789

EP - 791

JO - Stroke

JF - Stroke

SN - 0039-2499

IS - 3

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