MR lymphography for sentinel lymph node detection in patients with oral cavity cancer: Preliminary clinical study

Sohi Bae, Ho Joon Lee, Woong Nam, Yoon Woo Koh, Eun Chang Choi, Jinna Kim

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: The purpose of this study was to evaluate the feasibility of MR lymphography with interstitial injection of a gadolinium-based contrast agent for identifying sentinel lymph nodes in patients with oral cavity cancer and clinically negative neck. Methods: Pretreatment MR lymphography with a differential subsampling with cartesian ordering (DISCO) sequence was performed in 26 patients with resectable oral cavity cancer and clinically negative neck, after peritumoral injection of 1-mL diluted gadobutrol. The accuracy of sentinel lymph node identification by MR lymphography was assessed and compared with the final histopathological results. Results: The MR lymphography consistently visualized the 44 sentinel lymph nodes in all 26 patients. In all but 1 patient with pathologically positive neck, assumed sentinel lymph nodes revealed metastatic involvement. Conclusion: Pretreatment MR lymphography is a safe and feasible imaging technique that can help clinicians identify sentinel lymph nodes with a high risk of occult metastases in patients with oral cavity cancer, enabling focused preoperative biopsy in these high-risk patients.

Original languageEnglish
Pages (from-to)1483-1488
Number of pages6
JournalHead and Neck
Volume40
Issue number7
DOIs
Publication statusPublished - 2018 Jul

Fingerprint

Lymphography
Mouth Neoplasms
Mouth
Neck
Injections
Gadolinium
Contrast Media
Clinical Studies
Sentinel Lymph Node
Neoplasm Metastasis
Biopsy

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

Bae, Sohi ; Lee, Ho Joon ; Nam, Woong ; Koh, Yoon Woo ; Choi, Eun Chang ; Kim, Jinna. / MR lymphography for sentinel lymph node detection in patients with oral cavity cancer : Preliminary clinical study. In: Head and Neck. 2018 ; Vol. 40, No. 7. pp. 1483-1488.
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MR lymphography for sentinel lymph node detection in patients with oral cavity cancer : Preliminary clinical study. / Bae, Sohi; Lee, Ho Joon; Nam, Woong; Koh, Yoon Woo; Choi, Eun Chang; Kim, Jinna.

In: Head and Neck, Vol. 40, No. 7, 07.2018, p. 1483-1488.

Research output: Contribution to journalArticle

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