MREIT conductivity imaging of the postmortem canine abdomen using CoReHA

Kiwan Jeon, Atul S. Minhas, Young Tae Kim, Woo Chul Jeong, Hyung Joong Kim, Byeong Teck Kang, Hee Myung Park, Chang Ock Lee, Jin Keun Seo, Eung Je Woo

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Magnetic resonance electrical impedance tomography (MREIT) is a new bio-imaging modality providing cross-sectional conductivity images from measurements of internal magnetic flux densities produced by externally injected currents. Recent experimental results of postmortem and in vivo imaging of the canine brain demonstrated its feasibility by showing conductivity images with meaningful contrast among different brain tissues. MREIT image reconstructions involve a series of data processing steps such as k-space data handling, phase unwrapping, image segmentation, meshing, modelling, finite element computation, denoising and so on. To facilitate experimental studies, we need a software tool that automates these data processing steps. In this paper, we summarize such an MREIT software package called CoReHA (conductivity reconstructor using harmonic algorithms). Performing imaging experiments of the postmortem canine abdomen, we demonstrate how CoReHA can be utilized in MREIT. The abdomen with a relatively large field of view and various organs imposes new technical challenges when it is chosen as an imaging domain. Summarizing a few improvements in the experimental MREIT technique, we report our first conductivity images of the postmortem canine abdomen. Illustrating reconstructed conductivity images, we discuss how they discern different organs including the kidney, spleen, stomach and small intestine. We elaborate, as an example, that conductivity images of the kidney show clear contrast among cortex, internal medulla, renal pelvis and urethra. We end this paper with a brief discussion on future work using different animal models.

Original languageEnglish
Pages (from-to)957-966
Number of pages10
JournalPhysiological measurement
Volume30
Issue number9
DOIs
Publication statusPublished - 2009 Nov 4

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Physiology
  • Biomedical Engineering
  • Physiology (medical)

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    Jeon, K., Minhas, A. S., Kim, Y. T., Jeong, W. C., Kim, H. J., Kang, B. T., Park, H. M., Lee, C. O., Seo, J. K., & Woo, E. J. (2009). MREIT conductivity imaging of the postmortem canine abdomen using CoReHA. Physiological measurement, 30(9), 957-966. https://doi.org/10.1088/0967-3334/30/9/007