Mucous membrane pemphigoid with immunoglobulin G autoantibodies against full-length and 120-kDa ectodomain of BP180

Yuri Choi, Sang Eun Lee, Shunpei Fukuda, Takashi Hashimoto, Soo Chan Kim

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Mucous membrane pemphigoid (MMP) is a rare autoimmune, subepidermal, bullous disease characterized by erosive lesions on the mucous membranes and skin. MMP reacts with various target antigens including BP180, laminin-332, β4 integrin, α6 integrin or type VII collagen. We present a 67-year-old male MMP patient who had lesions on the oral and ocular mucous membranes and facial skin. By immunoblot analyses, immunoglobulin G autoantibodies in the patients sera reacted with full-length BP180 and the 120-kDa ectodomain of BP180 (LAD-1).

Original languageEnglish
Pages (from-to)169-172
Number of pages4
JournalJournal of Dermatology
Volume38
Issue number2
DOIs
Publication statusPublished - 2011 Feb

All Science Journal Classification (ASJC) codes

  • Dermatology

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