Multi-frequency time-difference complex conductivity imaging of canine and human lungs using the KHU Mark1 EIT system

Jihyeon Kuen, Eung Je Woo, Jin Keun Seo

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We evaluated the performance of the lately developed electrical impedance tomography (EIT) system KHU Mark1 through time-difference imaging experiments of canine and human lungs. We derived a multi-frequency time-difference EIT (mftdEIT) image reconstruction algorithm based on the concept of the equivalent homogeneous complex conductivity. Imaging experiments were carried out at three different frequencies of 10, 50 and 100 kHz with three different postures of right lateral, sitting (or prone) and left lateral positions. For three normal canine subjects, we controlled the ventilation using a ventilator at three tidal volumes of 100, 150 and 200 ml. Three human subjects were asked to breath spontaneously at a normal tidal volume. Real- and imaginary-part images of the canine and human lungs were reconstructed at three frequencies and three postures. Images showed different stages of breathing cycles and we could interpret them based on the understanding of the proposed mftdEIT image reconstruction algorithm. Time series of images were further analyzed by using the functional EIT (fEIT) method. Images of human subjects showed the gravity effect on air distribution in two lungs. In the canine subjects, the morphological change seems to dominate the gravity effect. We could also observe that two different types of ventilation should have affected the results. The KHU Mark1 EIT system is expected to provide reliable mftdEIT images of the human lungs. In terms of the image reconstruction algorithm, it would be worthwhile including the effects of three-dimensional current flows inside the human thorax. We suggest clinical trials of the KHU Mark1 for pulmonary applications.

Original languageEnglish
Pages (from-to)S149-S164
JournalPhysiological measurement
Volume30
Issue number6
DOIs
Publication statusPublished - 2009 Nov 4

Fingerprint

Acoustic impedance
Electric Impedance
Tomography
Canidae
Image reconstruction
Imaging techniques
Lung
Computer-Assisted Image Processing
Ventilation
Gravitation
Tidal Volume
Posture
Time series
Experiments
Mechanical Ventilators
Respiration
Thorax
Air
Clinical Trials

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Physiology
  • Biomedical Engineering
  • Physiology (medical)

Cite this

@article{6223991afbfc4cb9bfb12f8fc5c8b9c4,
title = "Multi-frequency time-difference complex conductivity imaging of canine and human lungs using the KHU Mark1 EIT system",
abstract = "We evaluated the performance of the lately developed electrical impedance tomography (EIT) system KHU Mark1 through time-difference imaging experiments of canine and human lungs. We derived a multi-frequency time-difference EIT (mftdEIT) image reconstruction algorithm based on the concept of the equivalent homogeneous complex conductivity. Imaging experiments were carried out at three different frequencies of 10, 50 and 100 kHz with three different postures of right lateral, sitting (or prone) and left lateral positions. For three normal canine subjects, we controlled the ventilation using a ventilator at three tidal volumes of 100, 150 and 200 ml. Three human subjects were asked to breath spontaneously at a normal tidal volume. Real- and imaginary-part images of the canine and human lungs were reconstructed at three frequencies and three postures. Images showed different stages of breathing cycles and we could interpret them based on the understanding of the proposed mftdEIT image reconstruction algorithm. Time series of images were further analyzed by using the functional EIT (fEIT) method. Images of human subjects showed the gravity effect on air distribution in two lungs. In the canine subjects, the morphological change seems to dominate the gravity effect. We could also observe that two different types of ventilation should have affected the results. The KHU Mark1 EIT system is expected to provide reliable mftdEIT images of the human lungs. In terms of the image reconstruction algorithm, it would be worthwhile including the effects of three-dimensional current flows inside the human thorax. We suggest clinical trials of the KHU Mark1 for pulmonary applications.",
author = "Jihyeon Kuen and Woo, {Eung Je} and Seo, {Jin Keun}",
year = "2009",
month = "11",
day = "4",
doi = "10.1088/0967-3334/30/6/S10",
language = "English",
volume = "30",
pages = "S149--S164",
journal = "Physiological Measurement",
issn = "0967-3334",
publisher = "IOP Publishing Ltd.",
number = "6",

}

Multi-frequency time-difference complex conductivity imaging of canine and human lungs using the KHU Mark1 EIT system. / Kuen, Jihyeon; Woo, Eung Je; Seo, Jin Keun.

In: Physiological measurement, Vol. 30, No. 6, 04.11.2009, p. S149-S164.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Multi-frequency time-difference complex conductivity imaging of canine and human lungs using the KHU Mark1 EIT system

AU - Kuen, Jihyeon

AU - Woo, Eung Je

AU - Seo, Jin Keun

PY - 2009/11/4

Y1 - 2009/11/4

N2 - We evaluated the performance of the lately developed electrical impedance tomography (EIT) system KHU Mark1 through time-difference imaging experiments of canine and human lungs. We derived a multi-frequency time-difference EIT (mftdEIT) image reconstruction algorithm based on the concept of the equivalent homogeneous complex conductivity. Imaging experiments were carried out at three different frequencies of 10, 50 and 100 kHz with three different postures of right lateral, sitting (or prone) and left lateral positions. For three normal canine subjects, we controlled the ventilation using a ventilator at three tidal volumes of 100, 150 and 200 ml. Three human subjects were asked to breath spontaneously at a normal tidal volume. Real- and imaginary-part images of the canine and human lungs were reconstructed at three frequencies and three postures. Images showed different stages of breathing cycles and we could interpret them based on the understanding of the proposed mftdEIT image reconstruction algorithm. Time series of images were further analyzed by using the functional EIT (fEIT) method. Images of human subjects showed the gravity effect on air distribution in two lungs. In the canine subjects, the morphological change seems to dominate the gravity effect. We could also observe that two different types of ventilation should have affected the results. The KHU Mark1 EIT system is expected to provide reliable mftdEIT images of the human lungs. In terms of the image reconstruction algorithm, it would be worthwhile including the effects of three-dimensional current flows inside the human thorax. We suggest clinical trials of the KHU Mark1 for pulmonary applications.

AB - We evaluated the performance of the lately developed electrical impedance tomography (EIT) system KHU Mark1 through time-difference imaging experiments of canine and human lungs. We derived a multi-frequency time-difference EIT (mftdEIT) image reconstruction algorithm based on the concept of the equivalent homogeneous complex conductivity. Imaging experiments were carried out at three different frequencies of 10, 50 and 100 kHz with three different postures of right lateral, sitting (or prone) and left lateral positions. For three normal canine subjects, we controlled the ventilation using a ventilator at three tidal volumes of 100, 150 and 200 ml. Three human subjects were asked to breath spontaneously at a normal tidal volume. Real- and imaginary-part images of the canine and human lungs were reconstructed at three frequencies and three postures. Images showed different stages of breathing cycles and we could interpret them based on the understanding of the proposed mftdEIT image reconstruction algorithm. Time series of images were further analyzed by using the functional EIT (fEIT) method. Images of human subjects showed the gravity effect on air distribution in two lungs. In the canine subjects, the morphological change seems to dominate the gravity effect. We could also observe that two different types of ventilation should have affected the results. The KHU Mark1 EIT system is expected to provide reliable mftdEIT images of the human lungs. In terms of the image reconstruction algorithm, it would be worthwhile including the effects of three-dimensional current flows inside the human thorax. We suggest clinical trials of the KHU Mark1 for pulmonary applications.

UR - http://www.scopus.com/inward/record.url?scp=70149098455&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70149098455&partnerID=8YFLogxK

U2 - 10.1088/0967-3334/30/6/S10

DO - 10.1088/0967-3334/30/6/S10

M3 - Article

C2 - 19491441

AN - SCOPUS:70149098455

VL - 30

SP - S149-S164

JO - Physiological Measurement

JF - Physiological Measurement

SN - 0967-3334

IS - 6

ER -