Abstract
We present herein the occurrence of multifocal adenocarcinomas with a minute signet ring cell carcinoma that arose within a gastric inverted hyperplastic polyp (IHP) in a 40-year-old woman. Endoscopic ultrasonography demonstrated a heterogeneous hypoechoic mass in the third layer of the gastric wall. The endoscopic submucosal dissection specimen measuring 3.5×3.2×1.8 cm was a well-circumscribed protruding lesion that had a slit-shaped cavity. Histologically, the lesion consisted mainly of endophytic proliferation of hyperplastic columnar cells resembling normal foveolar epithelium. In addition, six foci of adenocarcinomas and a minute focus of signet ring cell carcinoma were randomly distributed in the superficial and deep regions. The adenocarcinoma was gradually transitioning from dysplasia, while the signet ring cell carcinoma was surrounded by hyperplastic foveolar epithelium. This is the first report of a gastric IHP with multifocal intramucosal adenocarcinomas and a signet ring cell carcinoma, and endoscopic submucosal dissection is used to completely resect it.
| Original language | English |
|---|---|
| Pages (from-to) | 387-391 |
| Number of pages | 5 |
| Journal | Korean Journal of Pathology |
| Volume | 46 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2012 Oct 30 |
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All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
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Multifocal adenocarcinomas arising within a gastric inverted hyperplastic polyp. / Kim, Hyunsoo; Hwang, Eun Jung; Jang, Jae Young; Lee, Juhie; Kim, Youn Wha.
In: Korean Journal of Pathology, Vol. 46, No. 4, 30.10.2012, p. 387-391.Research output: Contribution to journal › Article
TY - JOUR
T1 - Multifocal adenocarcinomas arising within a gastric inverted hyperplastic polyp
AU - Kim, Hyunsoo
AU - Hwang, Eun Jung
AU - Jang, Jae Young
AU - Lee, Juhie
AU - Kim, Youn Wha
PY - 2012/10/30
Y1 - 2012/10/30
N2 - We present herein the occurrence of multifocal adenocarcinomas with a minute signet ring cell carcinoma that arose within a gastric inverted hyperplastic polyp (IHP) in a 40-year-old woman. Endoscopic ultrasonography demonstrated a heterogeneous hypoechoic mass in the third layer of the gastric wall. The endoscopic submucosal dissection specimen measuring 3.5×3.2×1.8 cm was a well-circumscribed protruding lesion that had a slit-shaped cavity. Histologically, the lesion consisted mainly of endophytic proliferation of hyperplastic columnar cells resembling normal foveolar epithelium. In addition, six foci of adenocarcinomas and a minute focus of signet ring cell carcinoma were randomly distributed in the superficial and deep regions. The adenocarcinoma was gradually transitioning from dysplasia, while the signet ring cell carcinoma was surrounded by hyperplastic foveolar epithelium. This is the first report of a gastric IHP with multifocal intramucosal adenocarcinomas and a signet ring cell carcinoma, and endoscopic submucosal dissection is used to completely resect it.
AB - We present herein the occurrence of multifocal adenocarcinomas with a minute signet ring cell carcinoma that arose within a gastric inverted hyperplastic polyp (IHP) in a 40-year-old woman. Endoscopic ultrasonography demonstrated a heterogeneous hypoechoic mass in the third layer of the gastric wall. The endoscopic submucosal dissection specimen measuring 3.5×3.2×1.8 cm was a well-circumscribed protruding lesion that had a slit-shaped cavity. Histologically, the lesion consisted mainly of endophytic proliferation of hyperplastic columnar cells resembling normal foveolar epithelium. In addition, six foci of adenocarcinomas and a minute focus of signet ring cell carcinoma were randomly distributed in the superficial and deep regions. The adenocarcinoma was gradually transitioning from dysplasia, while the signet ring cell carcinoma was surrounded by hyperplastic foveolar epithelium. This is the first report of a gastric IHP with multifocal intramucosal adenocarcinomas and a signet ring cell carcinoma, and endoscopic submucosal dissection is used to completely resect it.
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UR - http://www.scopus.com/inward/citedby.url?scp=84867841813&partnerID=8YFLogxK
U2 - 10.4132/KoreanJPathol.2012.46.4.387
DO - 10.4132/KoreanJPathol.2012.46.4.387
M3 - Article
VL - 46
SP - 387
EP - 391
JO - Journal of Pathology and Translational Medicine
JF - Journal of Pathology and Translational Medicine
SN - 2383-7837
IS - 4
ER -