TY - JOUR
T1 - Multimodal Stimuli-Responsive Poly(2-isopropyl-2-oxazoline) with Dual Molecular Logic Gate Operations
AU - Kim, Joo Ho
AU - Koo, Eunhye
AU - Ju, Sang Yong
AU - Jang, Woo Dong
N1 - Publisher Copyright:
© 2015 American Chemical Society.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2015/7/28
Y1 - 2015/7/28
N2 - Azobenzene end-functionalized telechelic POx (Az-POx-Az) was designed for as multimodal stimuli-responsive polymer. Az-POx-Az (0.25 g/L) in physiological saline (150 mM NaCl) phosphate buffered solution (10 mM PBS, pH 7.4) exhibited fully reversible trans-cis photoisomerism upon alternate irradiation with 365 and 254 nm UV light. The photoisomerization of the azobenzene moieties influenced the lower critical solution temperature (LCST), and the cis form exhibited a slightly higher LCST than the trans form. Circular dichroism measurements of Az-POx-Az with cyclodextrins (CDs) exhibited induced circular dichroism at the absorption band of the azobenzene moiety, indicating the formation of host-guest complexes between the azobenzene moieties in Az-POx-Az and the CDs. After formation of host-guest complexes consisting of the azobenzene moieties and the CDs, Az-POx-Az exhibited increased LCSTs. Interestingly, the LCSTs of Az-POx-Az with α-CD and β-CD moved in opposite directions upon photoisomerization. By the changing from the trans to cis form, Az-POx-Az with α-CD exhibited a decreased LCST; however, Az-POx-Az with β-CD exhibited an increased LCST. Using the interconversions between the transparent and turbid states of the Az-POx-Az solution, we could realize two different logic circuit modes using three different external stimuli, i.e., temperature, UV light, and cyclodextrins.
AB - Azobenzene end-functionalized telechelic POx (Az-POx-Az) was designed for as multimodal stimuli-responsive polymer. Az-POx-Az (0.25 g/L) in physiological saline (150 mM NaCl) phosphate buffered solution (10 mM PBS, pH 7.4) exhibited fully reversible trans-cis photoisomerism upon alternate irradiation with 365 and 254 nm UV light. The photoisomerization of the azobenzene moieties influenced the lower critical solution temperature (LCST), and the cis form exhibited a slightly higher LCST than the trans form. Circular dichroism measurements of Az-POx-Az with cyclodextrins (CDs) exhibited induced circular dichroism at the absorption band of the azobenzene moiety, indicating the formation of host-guest complexes between the azobenzene moieties in Az-POx-Az and the CDs. After formation of host-guest complexes consisting of the azobenzene moieties and the CDs, Az-POx-Az exhibited increased LCSTs. Interestingly, the LCSTs of Az-POx-Az with α-CD and β-CD moved in opposite directions upon photoisomerization. By the changing from the trans to cis form, Az-POx-Az with α-CD exhibited a decreased LCST; however, Az-POx-Az with β-CD exhibited an increased LCST. Using the interconversions between the transparent and turbid states of the Az-POx-Az solution, we could realize two different logic circuit modes using three different external stimuli, i.e., temperature, UV light, and cyclodextrins.
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U2 - 10.1021/acs.macromol.5b01046
DO - 10.1021/acs.macromol.5b01046
M3 - Article
AN - SCOPUS:84937831803
VL - 48
SP - 4951
EP - 4956
JO - Macromolecules
JF - Macromolecules
SN - 0024-9297
IS - 14
ER -