The applicability of graphene quantum dots (GQDs) for the in vitro and in vivo live imaging and tracking of different types of human stem cells is investigated. GQDs synthesized by the modified graphite intercalated compound method show efficient cellular uptake with improved biocompatibility and highly sensitive optical properties, indicating their feasibility as a bio-imaging probe for stem cell therapy.
Bibliographical noteFunding Information:
This work was supported by grants (HI13C1479 and HI14C1588) from the Korea Health Technology R&D Project funded by the Ministry of Health and Welfare, Republic of Korea. This research was also supported by Nano-Material Technology Development Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (MSIP) (2012M3A7B4049807) and by the Center for Advanced Soft-Electronics funded by the MSIP as Global Frontier (CASE-2013M3A6A5073173).
© The Royal Society of Chemistry 2016.
All Science Journal Classification (ASJC) codes
- Materials Science(all)