Multiple biological properties of macelignan and its pharmacological implications

Saswati Paul; Jae Kwan Hwang; Hahn Young Kim; Won Kyung Jeon; Chihye Chung; Jung Soo Han

doi:10.1007/s12272-013-0048-z

Multiple biological properties of macelignan and its pharmacological implications

Saswati Paul, Jae Kwan Hwang, Hahn Young Kim, Won Kyung Jeon, Chihye Chung, Jung Soo Han

Research output: Contribution to journal › Review article › peer-review

18 Citations (Scopus)

Abstract

Macelignan found in the nutmeg mace of Myristica fragrans obtains increasing attention as a new avenue in treating various diseases. Macelignan has been shown to possess a spectrum of pharmacological activities, including anti-bacterial, anti-inflammatory, anti-cancer, anti-diabetes, and hepatoprotective activities; recently, it has also been shown to have neuroprotective activities. This review summarizes the current research on the biological effects of macelignan derived from M. fragrans, with emphasis on the importance in understanding and treating complex diseases such as cancer and Alzheimer's disease.

Original language	English
Pages (from-to)	264-272
Number of pages	9
Journal	Archives of pharmacal research
Volume	36
Issue number	3
DOIs	https://doi.org/10.1007/s12272-013-0048-z
Publication status	Published - 2013 Mar

Bibliographical note

Funding Information:
Acknowledgments This paper was supported by Konkuk University research support program (2011)

All Science Journal Classification (ASJC) codes

Molecular Medicine
Drug Discovery
Organic Chemistry

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title = "Multiple biological properties of macelignan and its pharmacological implications",

abstract = "Macelignan found in the nutmeg mace of Myristica fragrans obtains increasing attention as a new avenue in treating various diseases. Macelignan has been shown to possess a spectrum of pharmacological activities, including anti-bacterial, anti-inflammatory, anti-cancer, anti-diabetes, and hepatoprotective activities; recently, it has also been shown to have neuroprotective activities. This review summarizes the current research on the biological effects of macelignan derived from M. fragrans, with emphasis on the importance in understanding and treating complex diseases such as cancer and Alzheimer's disease.",

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AU - Hwang, Jae Kwan

AU - Kim, Hahn Young

AU - Jeon, Won Kyung

AU - Chung, Chihye

AU - Han, Jung Soo

N1 - Funding Information: Acknowledgments This paper was supported by Konkuk University research support program (2011)

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