TY - JOUR
T1 - Multisource inverse-geometry CT. Part I. System concept and development
AU - De Man, Bruno
AU - Uribe, Jorge
AU - Baek, Jongduk
AU - Harrison, Dan
AU - Yin, Zhye
AU - Longtin, Randy
AU - Roy, Jaydeep
AU - Waters, Bill
AU - Wilson, Colin
AU - Short, Jonathan
AU - Inzinna, Lou
AU - Reynolds, Joseph
AU - Neculaes, V. Bogdan
AU - Frutschy, Kristopher
AU - Senzig, Bob
AU - Pelc, Norbert
N1 - Publisher Copyright:
© 2016 American Association of Physicists in Medicine.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Purpose: This paper presents an overview of multisource inverse-geometry computed tomography (IGCT) as well as the development of a gantry-based research prototype system. The development of the distributed x-ray source is covered in a companion paper [V. B. Neculaes et al., Multisource inverse-geometry CT. Part II. X-ray source design and prototype, Med. Phys. 43, 46174627 (2016)]. While progress updates of this development have been presented at conferences and in journal papers, this paper is the first comprehensive overview of the multisource inverse-geometry CT concept and prototype. The authors also provide a review of all previous IGCT related publications. Methods: The authors designed and implemented a gantry-based 32-source IGCT scanner with 22 cm field-of-view, 16 cm z-coverage, 1 s rotation time, 1.09×1.024 mm detector cell size, as low as 0.4×0.8 mm focal spot size and 80140 kVp x-ray source voltage. The system is built using commercially available CT components and a custom made distributed x-ray source. The authors developed dedicated controls, calibrations, and reconstruction algorithms and evaluated the system performance using phantoms and small animals. Results: The authors performed IGCT system experiments and demonstrated tube current up to 125 mA with up to 32 focal spots. The authors measured a spatial resolution of 13 lp/cm at 5% cutoff. The scatter-to-primary ratio is estimated 62% for a 32 cm water phantom at 140 kVp. The authors scanned several phantoms and small animals. The initial images have relatively high noise due to the low x-ray flux levels but minimal artifacts. Conclusions: IGCT has unique benefits in terms of dose-efficiency and cone-beam artifacts, but comes with challenges in terms of scattered radiation and x-ray flux limits. To the authors knowledge, their prototype is the first gantry-based IGCT scanner. The authors summarized the design and implementation of the scanner and the authors presented results with phantoms and small animals.
AB - Purpose: This paper presents an overview of multisource inverse-geometry computed tomography (IGCT) as well as the development of a gantry-based research prototype system. The development of the distributed x-ray source is covered in a companion paper [V. B. Neculaes et al., Multisource inverse-geometry CT. Part II. X-ray source design and prototype, Med. Phys. 43, 46174627 (2016)]. While progress updates of this development have been presented at conferences and in journal papers, this paper is the first comprehensive overview of the multisource inverse-geometry CT concept and prototype. The authors also provide a review of all previous IGCT related publications. Methods: The authors designed and implemented a gantry-based 32-source IGCT scanner with 22 cm field-of-view, 16 cm z-coverage, 1 s rotation time, 1.09×1.024 mm detector cell size, as low as 0.4×0.8 mm focal spot size and 80140 kVp x-ray source voltage. The system is built using commercially available CT components and a custom made distributed x-ray source. The authors developed dedicated controls, calibrations, and reconstruction algorithms and evaluated the system performance using phantoms and small animals. Results: The authors performed IGCT system experiments and demonstrated tube current up to 125 mA with up to 32 focal spots. The authors measured a spatial resolution of 13 lp/cm at 5% cutoff. The scatter-to-primary ratio is estimated 62% for a 32 cm water phantom at 140 kVp. The authors scanned several phantoms and small animals. The initial images have relatively high noise due to the low x-ray flux levels but minimal artifacts. Conclusions: IGCT has unique benefits in terms of dose-efficiency and cone-beam artifacts, but comes with challenges in terms of scattered radiation and x-ray flux limits. To the authors knowledge, their prototype is the first gantry-based IGCT scanner. The authors summarized the design and implementation of the scanner and the authors presented results with phantoms and small animals.
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U2 - 10.1118/1.4954846
DO - 10.1118/1.4954846
M3 - Article
C2 - 27487877
AN - SCOPUS:84978972845
VL - 43
SP - 4607
EP - 4616
JO - Medical Physics
JF - Medical Physics
SN - 0094-2405
IS - 8
ER -