Abstract
Seven new muurolane-type sesquiterpenes, (4R,5R)-muurol-1(6),10(14)-diene- 4,5-diol (1), (4R,5R)-muurol-1(6)-ene-4,5-diol (2), (4R,5R,10R)-10- methoxymuurol-1(6)-ene-4,5-diol (3), (4S)-4-hydroxy-1,10-seco-muurol-5-ene-1,10- dione (4), (4R)-4-hydroxy- 1,10-seco-muurol-5-ene-1,10-dione (5), (6S,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (6), and (6R,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12- oic acid (7) were isolated from the marine sponge Dysidea cinerea. Their structures were determined by the combination of spectroscopic and chemical methods, including 1D-NMR, 2D-NMR, and CD spectra as well as by comparing the NMR data with those reported in the literature.
| Original language | English |
|---|---|
| Pages (from-to) | 51-56 |
| Number of pages | 6 |
| Journal | Magnetic Resonance in Chemistry |
| Volume | 52 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - 2013 Jan 1 |
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All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Materials Science(all)
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Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea. / Van Kiem, Phan; Van Minh, Chau; Nhiem, Nguyen Xuan; Cuc, Nguyen Thi; Van Quang, Ngo; Anh, Hoang Le Tuan; Tai, Bui Huu; Yen, Pham Hai; Hoai, Nguyen Thi; Ho, Kim Young; Kim, Nanyoung; Park, Seon Ju; Kim, Seung Hyun.
In: Magnetic Resonance in Chemistry, Vol. 52, No. 1-2, 01.01.2013, p. 51-56.Research output: Contribution to journal › Article
TY - JOUR
T1 - Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea
AU - Van Kiem, Phan
AU - Van Minh, Chau
AU - Nhiem, Nguyen Xuan
AU - Cuc, Nguyen Thi
AU - Van Quang, Ngo
AU - Anh, Hoang Le Tuan
AU - Tai, Bui Huu
AU - Yen, Pham Hai
AU - Hoai, Nguyen Thi
AU - Ho, Kim Young
AU - Kim, Nanyoung
AU - Park, Seon Ju
AU - Kim, Seung Hyun
PY - 2013/1/1
Y1 - 2013/1/1
N2 - Seven new muurolane-type sesquiterpenes, (4R,5R)-muurol-1(6),10(14)-diene- 4,5-diol (1), (4R,5R)-muurol-1(6)-ene-4,5-diol (2), (4R,5R,10R)-10- methoxymuurol-1(6)-ene-4,5-diol (3), (4S)-4-hydroxy-1,10-seco-muurol-5-ene-1,10- dione (4), (4R)-4-hydroxy- 1,10-seco-muurol-5-ene-1,10-dione (5), (6S,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (6), and (6R,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12- oic acid (7) were isolated from the marine sponge Dysidea cinerea. Their structures were determined by the combination of spectroscopic and chemical methods, including 1D-NMR, 2D-NMR, and CD spectra as well as by comparing the NMR data with those reported in the literature.
AB - Seven new muurolane-type sesquiterpenes, (4R,5R)-muurol-1(6),10(14)-diene- 4,5-diol (1), (4R,5R)-muurol-1(6)-ene-4,5-diol (2), (4R,5R,10R)-10- methoxymuurol-1(6)-ene-4,5-diol (3), (4S)-4-hydroxy-1,10-seco-muurol-5-ene-1,10- dione (4), (4R)-4-hydroxy- 1,10-seco-muurol-5-ene-1,10-dione (5), (6S,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (6), and (6R,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12- oic acid (7) were isolated from the marine sponge Dysidea cinerea. Their structures were determined by the combination of spectroscopic and chemical methods, including 1D-NMR, 2D-NMR, and CD spectra as well as by comparing the NMR data with those reported in the literature.
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U2 - 10.1002/mrc.4030
DO - 10.1002/mrc.4030
M3 - Article
VL - 52
SP - 51
EP - 56
JO - Magnetic Resonance in Chemistry
JF - Magnetic Resonance in Chemistry
SN - 0749-1581
IS - 1-2
ER -