Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea

Phan Van Kiem, Chau Van Minh, Nguyen Xuan Nhiem, Nguyen Thi Cuc, Ngo Van Quang, Hoang Le Tuan Anh, Bui Huu Tai, Pham Hai Yen, Nguyen Thi Hoai, Kim Young Ho, Nanyoung Kim, Seon Ju Park, Seung Hyun Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Seven new muurolane-type sesquiterpenes, (4R,5R)-muurol-1(6),10(14)-diene- 4,5-diol (1), (4R,5R)-muurol-1(6)-ene-4,5-diol (2), (4R,5R,10R)-10- methoxymuurol-1(6)-ene-4,5-diol (3), (4S)-4-hydroxy-1,10-seco-muurol-5-ene-1,10- dione (4), (4R)-4-hydroxy- 1,10-seco-muurol-5-ene-1,10-dione (5), (6S,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (6), and (6R,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12- oic acid (7) were isolated from the marine sponge Dysidea cinerea. Their structures were determined by the combination of spectroscopic and chemical methods, including 1D-NMR, 2D-NMR, and CD spectra as well as by comparing the NMR data with those reported in the literature.

Original languageEnglish
Pages (from-to)51-56
Number of pages6
JournalMagnetic Resonance in Chemistry
Volume52
Issue number1-2
DOIs
Publication statusPublished - 2013 Jan 1

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Sesquiterpenes
Nuclear magnetic resonance
Acids

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Science(all)

Cite this

Van Kiem, P., Van Minh, C., Nhiem, N. X., Cuc, N. T., Van Quang, N., Anh, H. L. T., ... Kim, S. H. (2013). Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea. Magnetic Resonance in Chemistry, 52(1-2), 51-56. https://doi.org/10.1002/mrc.4030
Van Kiem, Phan ; Van Minh, Chau ; Nhiem, Nguyen Xuan ; Cuc, Nguyen Thi ; Van Quang, Ngo ; Anh, Hoang Le Tuan ; Tai, Bui Huu ; Yen, Pham Hai ; Hoai, Nguyen Thi ; Ho, Kim Young ; Kim, Nanyoung ; Park, Seon Ju ; Kim, Seung Hyun. / Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea. In: Magnetic Resonance in Chemistry. 2013 ; Vol. 52, No. 1-2. pp. 51-56.
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abstract = "Seven new muurolane-type sesquiterpenes, (4R,5R)-muurol-1(6),10(14)-diene- 4,5-diol (1), (4R,5R)-muurol-1(6)-ene-4,5-diol (2), (4R,5R,10R)-10- methoxymuurol-1(6)-ene-4,5-diol (3), (4S)-4-hydroxy-1,10-seco-muurol-5-ene-1,10- dione (4), (4R)-4-hydroxy- 1,10-seco-muurol-5-ene-1,10-dione (5), (6S,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (6), and (6R,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12- oic acid (7) were isolated from the marine sponge Dysidea cinerea. Their structures were determined by the combination of spectroscopic and chemical methods, including 1D-NMR, 2D-NMR, and CD spectra as well as by comparing the NMR data with those reported in the literature.",
author = "{Van Kiem}, Phan and {Van Minh}, Chau and Nhiem, {Nguyen Xuan} and Cuc, {Nguyen Thi} and {Van Quang}, Ngo and Anh, {Hoang Le Tuan} and Tai, {Bui Huu} and Yen, {Pham Hai} and Hoai, {Nguyen Thi} and Ho, {Kim Young} and Nanyoung Kim and Park, {Seon Ju} and Kim, {Seung Hyun}",
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Van Kiem, P, Van Minh, C, Nhiem, NX, Cuc, NT, Van Quang, N, Anh, HLT, Tai, BH, Yen, PH, Hoai, NT, Ho, KY, Kim, N, Park, SJ & Kim, SH 2013, 'Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea', Magnetic Resonance in Chemistry, vol. 52, no. 1-2, pp. 51-56. https://doi.org/10.1002/mrc.4030

Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea. / Van Kiem, Phan; Van Minh, Chau; Nhiem, Nguyen Xuan; Cuc, Nguyen Thi; Van Quang, Ngo; Anh, Hoang Le Tuan; Tai, Bui Huu; Yen, Pham Hai; Hoai, Nguyen Thi; Ho, Kim Young; Kim, Nanyoung; Park, Seon Ju; Kim, Seung Hyun.

In: Magnetic Resonance in Chemistry, Vol. 52, No. 1-2, 01.01.2013, p. 51-56.

Research output: Contribution to journalArticle

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T1 - Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea

AU - Van Kiem, Phan

AU - Van Minh, Chau

AU - Nhiem, Nguyen Xuan

AU - Cuc, Nguyen Thi

AU - Van Quang, Ngo

AU - Anh, Hoang Le Tuan

AU - Tai, Bui Huu

AU - Yen, Pham Hai

AU - Hoai, Nguyen Thi

AU - Ho, Kim Young

AU - Kim, Nanyoung

AU - Park, Seon Ju

AU - Kim, Seung Hyun

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Seven new muurolane-type sesquiterpenes, (4R,5R)-muurol-1(6),10(14)-diene- 4,5-diol (1), (4R,5R)-muurol-1(6)-ene-4,5-diol (2), (4R,5R,10R)-10- methoxymuurol-1(6)-ene-4,5-diol (3), (4S)-4-hydroxy-1,10-seco-muurol-5-ene-1,10- dione (4), (4R)-4-hydroxy- 1,10-seco-muurol-5-ene-1,10-dione (5), (6S,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (6), and (6R,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12- oic acid (7) were isolated from the marine sponge Dysidea cinerea. Their structures were determined by the combination of spectroscopic and chemical methods, including 1D-NMR, 2D-NMR, and CD spectra as well as by comparing the NMR data with those reported in the literature.

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Van Kiem P, Van Minh C, Nhiem NX, Cuc NT, Van Quang N, Anh HLT et al. Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea. Magnetic Resonance in Chemistry. 2013 Jan 1;52(1-2):51-56. https://doi.org/10.1002/mrc.4030