Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea

Phan Van Kiem, Chau Van Minh, Nguyen Xuan Nhiem, Nguyen Thi Cuc, Ngo Van Quang, Hoang Le Tuan Anh, Bui Huu Tai, Pham Hai Yen, Nguyen Thi Hoai, Kim Young Ho, Nanyoung Kim, Seon Ju Park, Seung Hyun Kim

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Abstract

Seven new muurolane-type sesquiterpenes, (4R,5R)-muurol-1(6),10(14)-diene- 4,5-diol (1), (4R,5R)-muurol-1(6)-ene-4,5-diol (2), (4R,5R,10R)-10- methoxymuurol-1(6)-ene-4,5-diol (3), (4S)-4-hydroxy-1,10-seco-muurol-5-ene-1,10- dione (4), (4R)-4-hydroxy- 1,10-seco-muurol-5-ene-1,10-dione (5), (6S,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (6), and (6R,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12- oic acid (7) were isolated from the marine sponge Dysidea cinerea. Their structures were determined by the combination of spectroscopic and chemical methods, including 1D-NMR, 2D-NMR, and CD spectra as well as by comparing the NMR data with those reported in the literature.

Original languageEnglish
Pages (from-to)51-56
Number of pages6
JournalMagnetic Resonance in Chemistry
Volume52
Issue number1-2
DOIs
Publication statusPublished - 2013 Jan 1

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Materials Science(all)

Cite this

Van Kiem, P., Van Minh, C., Nhiem, N. X., Cuc, N. T., Van Quang, N., Anh, H. L. T., Tai, B. H., Yen, P. H., Hoai, N. T., Ho, K. Y., Kim, N., Park, S. J., & Kim, S. H. (2013). Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea. Magnetic Resonance in Chemistry, 52(1-2), 51-56. https://doi.org/10.1002/mrc.4030