Nanographite impurities in carbon nanotubes: Their influence on the oxidation of insulin, nitric oxide, and extracellular thiols

Elaine Lay Khim Chng, Martin Pumera

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

There has been growing interest in the use of modified-carbonnanotube electrodes in applications such as the electrochemical detection of biologically significant compounds, owing to their apparent "electrocatalytic" properties and ability to enhance oxidative signals. In spite of their salient properties, little work has been done to further examine the reasons for these reported characteristics. In this report, we present clear evidence that the presence of nanographite impurities within carbon nanotubes (CNTs) is responsible for providing the previously reported enhanced electrochemical response. We have demonstrated this effect on homocysteine, Nacetyl- l-cysteine, nitric oxide, and insulin, which are important biological agents in the body. Moreover, we also showed that the influence of nanographite impurities on the electrochemistry of carbon nanotubes is prevalent among a variety of CNTs, such as single-walled CNTs, double-walled CNTs, and few-walled CNTs. Our findings will have a profound influence upon the biomedical applications of CNTs.

Original languageEnglish
Pages (from-to)1401-1407
Number of pages7
JournalChemistry - A European Journal
Volume18
Issue number5
DOIs
Publication statusPublished - 2012 Jan 27

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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