Abstract
We have studied the preparation and characterization of nanoporous thin films fabricated from a layer by layer assembly of branched poly(ethylene imine), gold nanoparticles (gold NPs) and hyaluronic acid. Gold NPs embedded in the multilayer thin film structure were easily dissolved using an aqueous cyanide solution, generating the nanoporous film. This allows for the direct and precise comparison of the porosity of the polymer based multilayer thin films in both the presence and the absence of gold NPs. Additionally, the layer by layer (LbL) assembly method has advantages in that it increases the possibilities for mass production of multilayer films, and allows the precise control of film structures prepared on large substrates. Therefore, this method offers a new route to allow the introduction of nanoporosity into multilayer thin films, allowing the development of more complex functional multicomponent nanoporous structures for protein delivery. Furthermore, these novel materials could be used in biomedical applications.
| Original language | English |
|---|---|
| Pages (from-to) | 221-225 |
| Number of pages | 5 |
| Journal | Journal of Industrial and Engineering Chemistry |
| Volume | 33 |
| DOIs | |
| Publication status | Published - 2016 Jan 25 |
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All Science Journal Classification (ASJC) codes
- Chemical Engineering(all)
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Nanoporous multilayer films for controlled antigen protein release. / Yang, Miso; Choi, Daheui; Choi, Moonhyun; Hong, Jinkee.
In: Journal of Industrial and Engineering Chemistry, Vol. 33, 25.01.2016, p. 221-225.Research output: Contribution to journal › Article
TY - JOUR
T1 - Nanoporous multilayer films for controlled antigen protein release
AU - Yang, Miso
AU - Choi, Daheui
AU - Choi, Moonhyun
AU - Hong, Jinkee
PY - 2016/1/25
Y1 - 2016/1/25
N2 - We have studied the preparation and characterization of nanoporous thin films fabricated from a layer by layer assembly of branched poly(ethylene imine), gold nanoparticles (gold NPs) and hyaluronic acid. Gold NPs embedded in the multilayer thin film structure were easily dissolved using an aqueous cyanide solution, generating the nanoporous film. This allows for the direct and precise comparison of the porosity of the polymer based multilayer thin films in both the presence and the absence of gold NPs. Additionally, the layer by layer (LbL) assembly method has advantages in that it increases the possibilities for mass production of multilayer films, and allows the precise control of film structures prepared on large substrates. Therefore, this method offers a new route to allow the introduction of nanoporosity into multilayer thin films, allowing the development of more complex functional multicomponent nanoporous structures for protein delivery. Furthermore, these novel materials could be used in biomedical applications.
AB - We have studied the preparation and characterization of nanoporous thin films fabricated from a layer by layer assembly of branched poly(ethylene imine), gold nanoparticles (gold NPs) and hyaluronic acid. Gold NPs embedded in the multilayer thin film structure were easily dissolved using an aqueous cyanide solution, generating the nanoporous film. This allows for the direct and precise comparison of the porosity of the polymer based multilayer thin films in both the presence and the absence of gold NPs. Additionally, the layer by layer (LbL) assembly method has advantages in that it increases the possibilities for mass production of multilayer films, and allows the precise control of film structures prepared on large substrates. Therefore, this method offers a new route to allow the introduction of nanoporosity into multilayer thin films, allowing the development of more complex functional multicomponent nanoporous structures for protein delivery. Furthermore, these novel materials could be used in biomedical applications.
UR - http://www.scopus.com/inward/record.url?scp=84951737937&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84951737937&partnerID=8YFLogxK
U2 - 10.1016/j.jiec.2015.10.009
DO - 10.1016/j.jiec.2015.10.009
M3 - Article
AN - SCOPUS:84951737937
VL - 33
SP - 221
EP - 225
JO - Journal of Industrial and Engineering Chemistry
JF - Journal of Industrial and Engineering Chemistry
SN - 1226-086X
ER -