Nanotechnology in corneal neovascularization therapy - A review

Lilian Gonzalez, Raymond J. Loza, Kyu Yeon Han, Suhair Sunoqrot, Christy Cunningham, Patryk Purta, James Drake, Sandeep Jain, Seungpyo Hong, Jin Hong Chang

Research output: Contribution to journalReview articlepeer-review

34 Citations (Scopus)


Nanotechnology is an up-And-coming branch of science that studies and designs materials with at least one dimension sized from 1-100 nm. These nanomaterials have unique functions at the cellular, atomic, and molecular levels.1 The term "nanotechnology" was first coined in 1974.2 Since then, it has evolved dramatically and now consists of distinct and independent scientific fields. Nanotechnology is a highly studied topic of interest, as nanoparticles can be applied to various fields ranging from medicine and pharmacology, to chemistry and agriculture, to environmental science and consumer goods.3 The rapidly evolving field of nanomedicine incorporates nanotechnology with medical applications, seeking to give rise to new diagnostic means, treatments, and tools. Over the past two decades, numerous studies that underscore the successful fusion of nanotechnology with novel medical applications have emerged. This has given rise to promising new therapies for a variety of diseases, especially cancer. It is becoming abundantly clear that nanotechnology has found a place in the medical field by providing new and more efficient ways to deliver treatment. Ophthalmology can also stand to benefit significantly from the advances in nanotechnology research. As it relates to the eye, research in the nanomedicine field has been particularly focused on developing various treatments to prevent and/or reduce corneal neovascularization among other ophthalmologic disorders. This review article aims to provide an overview of corneal neovascularization, currently available treatments, and where nanotechnology comes into play.

Original languageEnglish
Pages (from-to)124-134
Number of pages11
JournalJournal of Ocular Pharmacology and Therapeutics
Issue number2
Publication statusPublished - 2013 Mar 1

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Pharmacology
  • Pharmacology (medical)


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