The purpose of our study was to assess the cancer detection rate and positive predictive value (PPV) for incidentally detected abnormal axillary lymph nodes with negative mammography and subsequent breast ultrasound (US). We included 7039 screened patients (mean age, 52 y) from January 2012 to March 2015 with negative mammography and subsequent breast US results. In two patients with positive lymph nodes, neither were from breast malignancy. The calculated cancer detection rate, PPV for biopsy and axillary biopsy rate was 0.3 per 1000 axillary US, 14.3% and 0.2%. Cancer rates for patients with a family or personal operation history, with cancer history and with no family/operation/cancer history were 0%, 0.1% and 0.2%, respectively. Our results indicate that the cancer detection rate and PPV for US were too low to recommend routine axillary scanning including screening breast US in patients with negative mammography and subsequent breast US, especially with no history of any cancers.
|Number of pages||7|
|Journal||Ultrasound in Medicine and Biology|
|Publication status||Published - 2018 Jan|
Bibliographical noteFunding Information:
This study was supported by the Basic Science Research Program of the National Research Foundation of Korea funded by the Ministry of Science, ICT& Future Planning, Republic of Korea (grant 2013 R1 A1 A3013165 and 2017 R1 A2 B4010407 ); by a faculty research grant of Yonsei University College of Medicine for 2015(6-2015-0050) ; and by Research Institute of Radiologic Science, Yonsei University College of Medicine. The funding institutions had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. The institutional review board approved this retrospective observational study (IRB No.4-2016-0125).
All Science Journal Classification (ASJC) codes
- Radiological and Ultrasound Technology
- Acoustics and Ultrasonics