Necessity of radical hysterectomy for endometrial cancer patients with cervical invasion

Taek Sang Lee, Jae Weon Kim, Dae Yeon Kim, YoungTae Kim, Ki Heon Lee, Byoung Gie Kim, D. Scott McMeekin

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

To determine whether radical hysterectomy is necessary in the treatment of endometrial cancer patients with cervical involvement, we reviewed the medical records of women who underwent primary surgical treatment for endometrial carcinoma and selected patients with pathologically proven cervical invasion. Among 133 patients, 62 patients underwent extrafascial hysterectomy (EH) and 71 radical or modified radical hysterectomy (RH). The decision regarding EH or RH was made at the discretion of the attending surgeon. The sensitivity of pre-operative magnetic resonance imaging for cervical invasion was 44.7% (38/85). In RH patients, 10/71 (14.1%) patients had frankly histologic parametrial involvement (PMI). All were stage III or over. Eight of 10 patients had pelvic/paraaortic node metastasis and two showed extrauterine spread. In 74 patients with stage II cancer, RH was performed in 41 and PMI was not seen. Sixty-six (89.2%) patients had adjuvant radiation therapy and there were 3 patients who had developed recurrent disease in the RH group and none in the EH group (Mean follow-up: 51 months). Although these findings cannot conclusively refute or support the necessity of radical hysterectomy in patients with cervical extension, it is noteworthy that the risk of PMI seems to be minimal in patients with a tumor confined to the uterus without evidence of extrauterine spread.

Original languageEnglish
Pages (from-to)552-556
Number of pages5
JournalJournal of Korean medical science
Volume25
Issue number4
DOIs
Publication statusPublished - 2010 Apr 1

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Endometrial Neoplasms
Hysterectomy
Uterus
Medical Records
Neoplasms
Radiotherapy
Magnetic Resonance Imaging
Neoplasm Metastasis

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Lee, Taek Sang ; Kim, Jae Weon ; Kim, Dae Yeon ; Kim, YoungTae ; Lee, Ki Heon ; Kim, Byoung Gie ; McMeekin, D. Scott. / Necessity of radical hysterectomy for endometrial cancer patients with cervical invasion. In: Journal of Korean medical science. 2010 ; Vol. 25, No. 4. pp. 552-556.
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Necessity of radical hysterectomy for endometrial cancer patients with cervical invasion. / Lee, Taek Sang; Kim, Jae Weon; Kim, Dae Yeon; Kim, YoungTae; Lee, Ki Heon; Kim, Byoung Gie; McMeekin, D. Scott.

In: Journal of Korean medical science, Vol. 25, No. 4, 01.04.2010, p. 552-556.

Research output: Contribution to journalArticle

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