Abstract
Background The observer perspective causes patients with social anxiety disorder (SAD) to excessively inspect their performance and appearance. This study aimed to investigate the neural basis of distorted self-face recognition in non-social situations in patients with SAD. Methods Twenty patients with SAD and 20 age- and gender-matched healthy controls participated in this fMRI study. Data were acquired while participants performed a Composite Face Evaluation Task, during which they had to press a button indicating how much they liked a series of self-faces, attractively transformed self-faces, and attractive others’ faces. Results Patients had a tendency to show more favorable responses to the self-face and unfavorable responses to the others’ faces compared with controls, but the two groups’ responses to the attractively transformed self-faces did not differ. Significant group differences in regional activity were observed in the middle frontal and supramarginal gyri in the self-face condition (patients < controls); the inferior frontal gyrus in the attractively transformed self-face condition (patients > controls); and the middle frontal, supramarginal, and angular gyri in the attractive others’ face condition (patients > controls). Most fronto-parietal activities during observation of the self-face were negatively correlated with preference scores in patients but not in controls. Conclusion Patients with SAD have a positive point of view of their own face and experience self-relevance for the attractively transformed self-faces. This distorted cognition may be based on dysfunctions in the frontal and inferior parietal regions. The abnormal engagement of the fronto-parietal attentional network during processing face stimuli in non-social situations may be linked to distorted self-recognition in SAD.
| Original language | English |
|---|---|
| Pages (from-to) | 956-964 |
| Number of pages | 9 |
| Journal | NeuroImage: Clinical |
| Volume | 12 |
| DOIs | |
| Publication status | Published - 2015 Nov 11 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
- Neurology
- Clinical Neurology
- Cognitive Neuroscience
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Neural basis of distorted self-face recognition in social anxiety disorder. / Kim, Min Kyeong; Yoon, Hyung Jun; Shin, Yu Bin; Lee, Seung Koo; Kim, Jae-Jin.
In: NeuroImage: Clinical, Vol. 12, 11.11.2015, p. 956-964.Research output: Contribution to journal › Article
TY - JOUR
T1 - Neural basis of distorted self-face recognition in social anxiety disorder
AU - Kim, Min Kyeong
AU - Yoon, Hyung Jun
AU - Shin, Yu Bin
AU - Lee, Seung Koo
AU - Kim, Jae-Jin
PY - 2015/11/11
Y1 - 2015/11/11
N2 - Background The observer perspective causes patients with social anxiety disorder (SAD) to excessively inspect their performance and appearance. This study aimed to investigate the neural basis of distorted self-face recognition in non-social situations in patients with SAD. Methods Twenty patients with SAD and 20 age- and gender-matched healthy controls participated in this fMRI study. Data were acquired while participants performed a Composite Face Evaluation Task, during which they had to press a button indicating how much they liked a series of self-faces, attractively transformed self-faces, and attractive others’ faces. Results Patients had a tendency to show more favorable responses to the self-face and unfavorable responses to the others’ faces compared with controls, but the two groups’ responses to the attractively transformed self-faces did not differ. Significant group differences in regional activity were observed in the middle frontal and supramarginal gyri in the self-face condition (patients < controls); the inferior frontal gyrus in the attractively transformed self-face condition (patients > controls); and the middle frontal, supramarginal, and angular gyri in the attractive others’ face condition (patients > controls). Most fronto-parietal activities during observation of the self-face were negatively correlated with preference scores in patients but not in controls. Conclusion Patients with SAD have a positive point of view of their own face and experience self-relevance for the attractively transformed self-faces. This distorted cognition may be based on dysfunctions in the frontal and inferior parietal regions. The abnormal engagement of the fronto-parietal attentional network during processing face stimuli in non-social situations may be linked to distorted self-recognition in SAD.
AB - Background The observer perspective causes patients with social anxiety disorder (SAD) to excessively inspect their performance and appearance. This study aimed to investigate the neural basis of distorted self-face recognition in non-social situations in patients with SAD. Methods Twenty patients with SAD and 20 age- and gender-matched healthy controls participated in this fMRI study. Data were acquired while participants performed a Composite Face Evaluation Task, during which they had to press a button indicating how much they liked a series of self-faces, attractively transformed self-faces, and attractive others’ faces. Results Patients had a tendency to show more favorable responses to the self-face and unfavorable responses to the others’ faces compared with controls, but the two groups’ responses to the attractively transformed self-faces did not differ. Significant group differences in regional activity were observed in the middle frontal and supramarginal gyri in the self-face condition (patients < controls); the inferior frontal gyrus in the attractively transformed self-face condition (patients > controls); and the middle frontal, supramarginal, and angular gyri in the attractive others’ face condition (patients > controls). Most fronto-parietal activities during observation of the self-face were negatively correlated with preference scores in patients but not in controls. Conclusion Patients with SAD have a positive point of view of their own face and experience self-relevance for the attractively transformed self-faces. This distorted cognition may be based on dysfunctions in the frontal and inferior parietal regions. The abnormal engagement of the fronto-parietal attentional network during processing face stimuli in non-social situations may be linked to distorted self-recognition in SAD.
UR - http://www.scopus.com/inward/record.url?scp=84973659179&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84973659179&partnerID=8YFLogxK
U2 - 10.1016/j.nicl.2016.04.010
DO - 10.1016/j.nicl.2016.04.010
M3 - Article
C2 - 27995061
AN - SCOPUS:84973659179
VL - 12
SP - 956
EP - 964
JO - NeuroImage: Clinical
JF - NeuroImage: Clinical
SN - 2213-1582
ER -