Neural stem cell differentiation in vascular microenvironment

Sewoon Han, Yoojin Shin, Hyo Eun Jeong, Kisuk Yang, Roger D. Kamm, Seung Woo Cho, Seok Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Here, we present a novel method to create in v/vo-like vascular microenvironment of neural stem cell (NSC) and to quantify the influences of three-dimensional vascular microenvironment for guiding the differentiation of NSCs embedded in extracellular matrix using quantitative real-time polymerase chain reaction (qRT-PCR). Using our new assay we found that NSC differentiation in reconstituted vascular microenvironment differs from the one in macro in vitro system (Qin Shen et al., Science. 2004).

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages210-212
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: 2012 Oct 282012 Nov 1

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period12/10/2812/11/1

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Han, S., Shin, Y., Jeong, H. E., Yang, K., Kamm, R. D., Cho, S. W., & Chung, S. (2012). Neural stem cell differentiation in vascular microenvironment. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 (pp. 210-212). (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012). Chemical and Biological Microsystems Society.