Neurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy

Yun Jin Lee, Hoon Chul Kang, Heung Dong Kim, Dong Seok Kim, Kyu Won Shim, Soyong Eom, Joon Soo Lee

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background We assessed the postoperative neurocognitive function after temporal lobectomy in children with temporal lobe epilepsy. Methods This was a retrospective analysis of the data of 20 patients with Engel's class I or II outcomes after anterior temporal lobectomy with amygdalohippocampectomy between 2005 and 2008. Twenty children underwent resection of either dominant (n = 8) or nondominant (n = 12) temporal lobes, and their median age at surgery was 12.8 ± 3.2 years. We serially assessed intelligence and memory function as measured by the Korean-Wechsler Scales of Intelligence and Rey-Kim Memory test both before and after surgery. Results Intelligence quotient (IQ) and memory quotient scores remained stable during a 3.6-year median follow-up in these children after the surgery. There was no decrease of IQ or memory quotient scores in either the dominant or non-dominant hemisphere groups. Later onset of epilepsy, a shorter epilepsy duration, a smaller number of antiepileptic drugs, and postoperative seizure-free outcomes were significant good predictors of the postoperative IQ. Conclusion Temporal lobectomy in children did not provoke a significant decline in intelligence or memory function. Early surgical treatment in children with intractable seizures of temporal lobe origin may result in better neurocognitive outcomes.

Original languageEnglish
Pages (from-to)88-93
Number of pages6
JournalPediatric Neurology
Volume52
Issue number1
DOIs
Publication statusPublished - 2015 Jan 1

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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