Neurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy

Yun Jin Lee, hoonchul kang, HeungDong Kim, Dong Seok Kim, Kyu Won Shim, Soyong Eom, Joon Soo Lee

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background We assessed the postoperative neurocognitive function after temporal lobectomy in children with temporal lobe epilepsy. Methods This was a retrospective analysis of the data of 20 patients with Engel's class I or II outcomes after anterior temporal lobectomy with amygdalohippocampectomy between 2005 and 2008. Twenty children underwent resection of either dominant (n = 8) or nondominant (n = 12) temporal lobes, and their median age at surgery was 12.8 ± 3.2 years. We serially assessed intelligence and memory function as measured by the Korean-Wechsler Scales of Intelligence and Rey-Kim Memory test both before and after surgery. Results Intelligence quotient (IQ) and memory quotient scores remained stable during a 3.6-year median follow-up in these children after the surgery. There was no decrease of IQ or memory quotient scores in either the dominant or non-dominant hemisphere groups. Later onset of epilepsy, a shorter epilepsy duration, a smaller number of antiepileptic drugs, and postoperative seizure-free outcomes were significant good predictors of the postoperative IQ. Conclusion Temporal lobectomy in children did not provoke a significant decline in intelligence or memory function. Early surgical treatment in children with intractable seizures of temporal lobe origin may result in better neurocognitive outcomes.

Original languageEnglish
Pages (from-to)88-93
Number of pages6
JournalPediatric Neurology
Volume52
Issue number1
DOIs
Publication statusPublished - 2015 Jan 1

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Anterior Temporal Lobectomy
Intelligence
Temporal Lobe
Epilepsy
Seizures
Wechsler Scales
Temporal Lobe Epilepsy
Anticonvulsants

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology
  • Medicine(all)

Cite this

Lee, Yun Jin ; kang, hoonchul ; Kim, HeungDong ; Kim, Dong Seok ; Shim, Kyu Won ; Eom, Soyong ; Lee, Joon Soo. / Neurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy. In: Pediatric Neurology. 2015 ; Vol. 52, No. 1. pp. 88-93.
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abstract = "Background We assessed the postoperative neurocognitive function after temporal lobectomy in children with temporal lobe epilepsy. Methods This was a retrospective analysis of the data of 20 patients with Engel's class I or II outcomes after anterior temporal lobectomy with amygdalohippocampectomy between 2005 and 2008. Twenty children underwent resection of either dominant (n = 8) or nondominant (n = 12) temporal lobes, and their median age at surgery was 12.8 ± 3.2 years. We serially assessed intelligence and memory function as measured by the Korean-Wechsler Scales of Intelligence and Rey-Kim Memory test both before and after surgery. Results Intelligence quotient (IQ) and memory quotient scores remained stable during a 3.6-year median follow-up in these children after the surgery. There was no decrease of IQ or memory quotient scores in either the dominant or non-dominant hemisphere groups. Later onset of epilepsy, a shorter epilepsy duration, a smaller number of antiepileptic drugs, and postoperative seizure-free outcomes were significant good predictors of the postoperative IQ. Conclusion Temporal lobectomy in children did not provoke a significant decline in intelligence or memory function. Early surgical treatment in children with intractable seizures of temporal lobe origin may result in better neurocognitive outcomes.",
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Neurocognitive function in children after anterior temporal lobectomy with amygdalohippocampectomy. / Lee, Yun Jin; kang, hoonchul; Kim, HeungDong; Kim, Dong Seok; Shim, Kyu Won; Eom, Soyong; Lee, Joon Soo.

In: Pediatric Neurology, Vol. 52, No. 1, 01.01.2015, p. 88-93.

Research output: Contribution to journalArticle

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N2 - Background We assessed the postoperative neurocognitive function after temporal lobectomy in children with temporal lobe epilepsy. Methods This was a retrospective analysis of the data of 20 patients with Engel's class I or II outcomes after anterior temporal lobectomy with amygdalohippocampectomy between 2005 and 2008. Twenty children underwent resection of either dominant (n = 8) or nondominant (n = 12) temporal lobes, and their median age at surgery was 12.8 ± 3.2 years. We serially assessed intelligence and memory function as measured by the Korean-Wechsler Scales of Intelligence and Rey-Kim Memory test both before and after surgery. Results Intelligence quotient (IQ) and memory quotient scores remained stable during a 3.6-year median follow-up in these children after the surgery. There was no decrease of IQ or memory quotient scores in either the dominant or non-dominant hemisphere groups. Later onset of epilepsy, a shorter epilepsy duration, a smaller number of antiepileptic drugs, and postoperative seizure-free outcomes were significant good predictors of the postoperative IQ. Conclusion Temporal lobectomy in children did not provoke a significant decline in intelligence or memory function. Early surgical treatment in children with intractable seizures of temporal lobe origin may result in better neurocognitive outcomes.

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