Neurological, Psychiatric, and Psychological Implications of the COVID-19 Pandemic: Protocol for a Large-Scale Umbrella Review of Observational Studies

Ta Chuan Yeh, Chih Sung Liang, Chia Kuang Tsai, Marco Solmi, Beny Lafer, Ping Tao Tseng, Chih Wei Hsu, Pao Yen Lin, Joseph Firth, Brendon Stubbs, Lamiece Hassan, Michele Fornaro, Eduard Vieta, Trevor Thompson, Jae Il Shin, Andre F. Carvalho

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The severe acute respiratory syndrome coronavirus 2 disease (SARS-CoV-2) is the most severe manifestation of the coronavirus disease 2019 (COVID-19) pandemic. Accruing evidence in-dicates that the COVID-19 pandemic may have profound deleterious neurological, psychiatric, and psychological outcomes. The number of systematic reviews (SRs) and meta-analyses (MAs) on this topic has grown exponentially. This protocol aims to synthesize all evidence from SRs and MAs on the associations between the COVID-19 pandemic and neuropsychiatric outcomes. The following electronic databases will be systematically searched from inception up to 15 January 2022: PubMed, Embase, APA PsycINFO, and Cochrane Reviews. An umbrella review (UR) of SRs and MAs of observational studies will be conducted. SRs and/or MAs of observational studies examining any direct or indirect association of COVID-19 with the neuropsychiatric outcomes will be deemed eligible for potential inclusion in this UR. The direct associations include the impact on the (1) prognosis of COVID-19 and (2) neuropsychiatric sequelae after COVID-19 infection. The indirect associations include the influence of the COVID-19 pandemic on the (1) treatments and (2) outcomes of neurological and psychiatric conditions associated with the COVID-19 pandemic.

Original languageEnglish
Article number1681
JournalInternational journal of environmental research and public health
Volume19
Issue number3
DOIs
Publication statusPublished - 2022 Feb 1

Bibliographical note

Funding Information:
Funding: The study was supported by from the Ministry of Science and Technology (MOST-110-2314-B-016-035-to C.-K.T.) and from Tri-Service General Hospital Penghu Branch (TSGH-PH-E-110011 to T.-C.Y.). The funding source had no role in any process of our study.

Publisher Copyright:
© 2022 by the authors. Li-censee MDPI, Basel, Switzerland.

All Science Journal Classification (ASJC) codes

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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