New markers in metabolic syndrome

Da Hye Son, Hyun Su Ha, Hye Min Park, Hae Young Kim, Yong Jae Lee

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


Metabolic syndrome (MetS) is increasing globally and is clinically significant due to its association with cardiovascular disease, type 2 diabetes and cancer. Although the pathogenesis of MetS has not been clearly elucidated, insulin resistance and chronic low-grade inflammation derived from central obesity are the most widely accepted as underlying pathophysiology. Accordingly, insulin resistance indices, adipokines and various inflammatory markers have been suggested as reliable biomarkers for MetS. Others, such as uric acid, alkaline phosphatase, γ-glutamyl transferase, are also known to positively correlate with MetS and could be diagnostically useful. In this review, we provide a comprehensive overview of MetS biomarkers and the development of a systematic approach to laboratory analysis.

Original languageEnglish
Title of host publicationAdvances in Clinical Chemistry
EditorsGregory S. Makowski, Gregory S. Makowski
PublisherAcademic Press Inc.
Number of pages35
ISBN (Print)9780323988537
Publication statusPublished - 2022 Jan

Publication series

NameAdvances in Clinical Chemistry
ISSN (Print)0065-2423
ISSN (Electronic)2162-9471

Bibliographical note

Publisher Copyright:
© 2022 Elsevier Inc.

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Clinical Biochemistry


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