This overview covers important aspects of microfluidic chip platforms as new materials for electrochemical (EC) sensing. It describes important trends in constructing detectors and their electronics on microfluidic chip platforms, the importance of selecting appropriate detector materials, and the different detection modes in on-chip amperometry, conductometry and potentiometry. We pay particular attention to the latest developments and to the fundamental issues of on-chip EC detection. We also discuss important applications of microfluidic chip platforms in genomic, security and environmental applications.
Bibliographical noteFunding Information:
This work was financially supported by the Spanish “Ramón Areces” Foundation (Project ‘Bionanosensores’), MEC (Madrid) (Projects BIO2004-02776, MAT2004-05164), and the “Ramón y Cajal” Program of the Ministry of Science and Technology (Madrid) supports A. Merkoçi. M. Pumera is grateful for support from the Marie Curie Intra-European Fellowship from European Community under the 6 th Framework Program (Project MEIF-CT-2004-005738).
All Science Journal Classification (ASJC) codes
- Analytical Chemistry