TY - JOUR
T1 - New-onset atrial fibrillation predicts long-term newly developed atrial fibrillation after coronary artery bypass graft
AU - Lee, Seung Hyun
AU - Kang, Dae Ryong
AU - Uhm, Jae Sun
AU - Shim, Jaemin
AU - Sung, Jung Hoon
AU - Kim, Jong Youn
AU - Pak, Hui Nam
AU - Lee, Moon Hyoung
AU - Joung, Boyoung
PY - 2014/4
Y1 - 2014/4
N2 - Background New-onset postoperative atrial fibrillation (POAF) is associated with poor short- and long-term outcomes after isolated coronary artery bypass graft (CABG). This study evaluated whether new-onset POAF is independently associated with long-term (>1 year) atrial fibrillation (AF) and mortality. Methods Among 1,171 consecutive patients who had undergone CABG, AF and mortality were compared between patients with POAF (POAF group, n = 244) and those without POAF (no-POAF group, n = 927) after propensity score matching. Results During the follow-up period of 41 ± 23 months (range 0-87 months), the POAF group had a higher incidence of total (20/927 [2.2%] vs 46/244 [18.9%], P <.001) and long-term AF recurrence (13/927 [1.4%] vs 25/244 [10.2%], P <.001). Even after propensity score matching, the POAF group still showed a higher incidence of total (7/244 [2.9%] vs 46/224 [18.9%], P <.001) and long-term AF recurrence (4/244 [1.6%] vs 25/224 [10.2%], P <.001). In addition, the POAF group had a lower cumulative survival free of long-term AF than the no-POAF group (P <.001). In competing risk regression, POAF was an independent predictor of long-term newly developed AF (hazard ratio 4.99, 95% CI 1.68-14.84, P =.004). Cumulative survival free of death was worse in patients with POAF (P =.01). Conclusions New-onset POAF was shown to be a predictor of long-term newly developed AF in CABG patients. The results of this study suggest that patients who develop POAF should undergo strict surveillance and routine screening for AF during follow-up after surgery.
AB - Background New-onset postoperative atrial fibrillation (POAF) is associated with poor short- and long-term outcomes after isolated coronary artery bypass graft (CABG). This study evaluated whether new-onset POAF is independently associated with long-term (>1 year) atrial fibrillation (AF) and mortality. Methods Among 1,171 consecutive patients who had undergone CABG, AF and mortality were compared between patients with POAF (POAF group, n = 244) and those without POAF (no-POAF group, n = 927) after propensity score matching. Results During the follow-up period of 41 ± 23 months (range 0-87 months), the POAF group had a higher incidence of total (20/927 [2.2%] vs 46/244 [18.9%], P <.001) and long-term AF recurrence (13/927 [1.4%] vs 25/244 [10.2%], P <.001). Even after propensity score matching, the POAF group still showed a higher incidence of total (7/244 [2.9%] vs 46/224 [18.9%], P <.001) and long-term AF recurrence (4/244 [1.6%] vs 25/224 [10.2%], P <.001). In addition, the POAF group had a lower cumulative survival free of long-term AF than the no-POAF group (P <.001). In competing risk regression, POAF was an independent predictor of long-term newly developed AF (hazard ratio 4.99, 95% CI 1.68-14.84, P =.004). Cumulative survival free of death was worse in patients with POAF (P =.01). Conclusions New-onset POAF was shown to be a predictor of long-term newly developed AF in CABG patients. The results of this study suggest that patients who develop POAF should undergo strict surveillance and routine screening for AF during follow-up after surgery.
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U2 - 10.1016/j.ahj.2013.12.010
DO - 10.1016/j.ahj.2013.12.010
M3 - Article
C2 - 24655710
AN - SCOPUS:84897072773
SN - 0002-8703
VL - 167
SP - 593-600.e1
JO - American Heart Journal
JF - American Heart Journal
IS - 4
ER -