Non-Hodgkin's lymphoma & primary biliary cirrhosis with Sjögren's syndrome.

J. S. Hahn, C. Kim, Y. H. Min, Y. W. Ko, C. O. Suh, Y. Y. Park

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Sjögren's syndrome (SS) is an autoimmune disease characterized by a lymphocytic infiltration of the salivary and lacrimal glands leading to a progressive destruction of these glands due to the production of autoantibodies. This disorder is either isolated (primary SS) or associated with other systemic diseases (secondary SS). The occurrence of B-cell non-Hodgkin's lymphoma (NHL) represents the major complication in the evolution of SS patients. The risk of developing NHL, which is equivalent for both primary and secondary SS, was estimated to be 44 times greater than that observed in a comparable normal population. NHLs in SS patients occur preferentially in the salivary glands and in other mucosa-associated lymphoid tissues (MALT). However, it can also occur in the lymph nodes or bone marrow. We documented a case of low-grade B-cell lymphoma of MALT in the right eyelid and primary biliary cirrhosis (PBC) of a patient with SS. To the best of our knowledge, this is the first case reported in Korea.

Original languageEnglish
Pages (from-to)258-263
Number of pages6
JournalYonsei medical journal
Volume42
Issue number2
DOIs
Publication statusPublished - 2001 Apr

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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