Non-invasive analysis of trabecular microstructural and biomechanical properties in obese OLETF rats

Myong Hyun Baek, Yoon Sok Chung, Ye Yeon Won, Wen Quan Cui, Hak Kyun Kim, Choon Hee Chung, Seung Hyun Yoo, Kwang Kyun Kim

Research output: Contribution to journalArticle

Abstract

Investigation of the bone mineral density (BMD), microstructural and mechanical properties in the Otsuka Long Evans Tokushima Fatty (OLETF) and Otsuka Long Evans Tokushima Fatty (LETO) rats were performed. The BMD and microstructural analyses were carried out using PIXI-mus and non-invasive high-resolution micro-computed tomography (micro-CT) system. The mechanical properties analyses were determined by finite element analysis based on micro-images. The BMD was significantly larger in LETO rat than in OLETF rat. The microstructural and mechanical properties were deteriorated and decreased in OLETF rat. The results showed that bone strength is decreased in OLETF in spite of high body weight.

Original languageEnglish
Pages (from-to)1129-1132
Number of pages4
JournalKey Engineering Materials
Volume321-323 II
DOIs
Publication statusPublished - 2006 Jan 1

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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    Baek, M. H., Chung, Y. S., Won, Y. Y., Cui, W. Q., Kim, H. K., Chung, C. H., Yoo, S. H., & Kim, K. K. (2006). Non-invasive analysis of trabecular microstructural and biomechanical properties in obese OLETF rats. Key Engineering Materials, 321-323 II, 1129-1132. https://doi.org/10.4028/0-87849-412-x.1129