Non-invasive analysis of trabecular microstructural and biomechanical properties in obese OLETF rats

Myong Hyun Baek; Yoon Sok Chung; Ye Yeon Won; Wen Quan Cui; Hak Kyun Kim; Choon Hee Chung; Seung Hyun Yoo; Kwang Kyun Kim

doi:10.4028/0-87849-412-x.1129

Non-invasive analysis of trabecular microstructural and biomechanical properties in obese OLETF rats

Myong Hyun Baek, Yoon Sok Chung, Ye Yeon Won, Wen Quan Cui, Hak Kyun Kim, Choon Hee Chung, Seung Hyun Yoo, Kwang Kyun Kim

Internal Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Investigation of the bone mineral density (BMD), microstructural and mechanical properties in the Otsuka Long Evans Tokushima Fatty (OLETF) and Otsuka Long Evans Tokushima Fatty (LETO) rats were performed. The BMD and microstructural analyses were carried out using PIXI-mus and non-invasive high-resolution micro-computed tomography (micro-CT) system. The mechanical properties analyses were determined by finite element analysis based on micro-images. The BMD was significantly larger in LETO rat than in OLETF rat. The microstructural and mechanical properties were deteriorated and decreased in OLETF rat. The results showed that bone strength is decreased in OLETF in spite of high body weight.

Original language	English
Pages (from-to)	1129-1132
Number of pages	4
Journal	Key Engineering Materials
Volume	321-323 II
DOIs	https://doi.org/10.4028/0-87849-412-x.1129
Publication status	Published - 2006

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.4028/0-87849-412-x.1129

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title = "Non-invasive analysis of trabecular microstructural and biomechanical properties in obese OLETF rats",

abstract = "Investigation of the bone mineral density (BMD), microstructural and mechanical properties in the Otsuka Long Evans Tokushima Fatty (OLETF) and Otsuka Long Evans Tokushima Fatty (LETO) rats were performed. The BMD and microstructural analyses were carried out using PIXI-mus and non-invasive high-resolution micro-computed tomography (micro-CT) system. The mechanical properties analyses were determined by finite element analysis based on micro-images. The BMD was significantly larger in LETO rat than in OLETF rat. The microstructural and mechanical properties were deteriorated and decreased in OLETF rat. The results showed that bone strength is decreased in OLETF in spite of high body weight.",

author = "Baek, {Myong Hyun} and Chung, {Yoon Sok} and Won, {Ye Yeon} and Cui, {Wen Quan} and Kim, {Hak Kyun} and Chung, {Choon Hee} and Yoo, {Seung Hyun} and Kim, {Kwang Kyun}",

year = "2006",

doi = "10.4028/0-87849-412-x.1129",

language = "English",

volume = "321-323 II",

pages = "1129--1132",

journal = "Key Engineering Materials",

issn = "1013-9826",

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TY - JOUR

T1 - Non-invasive analysis of trabecular microstructural and biomechanical properties in obese OLETF rats

AU - Baek, Myong Hyun

AU - Chung, Yoon Sok

AU - Won, Ye Yeon

AU - Cui, Wen Quan

AU - Kim, Hak Kyun

AU - Chung, Choon Hee

AU - Yoo, Seung Hyun

AU - Kim, Kwang Kyun

PY - 2006

Y1 - 2006

N2 - Investigation of the bone mineral density (BMD), microstructural and mechanical properties in the Otsuka Long Evans Tokushima Fatty (OLETF) and Otsuka Long Evans Tokushima Fatty (LETO) rats were performed. The BMD and microstructural analyses were carried out using PIXI-mus and non-invasive high-resolution micro-computed tomography (micro-CT) system. The mechanical properties analyses were determined by finite element analysis based on micro-images. The BMD was significantly larger in LETO rat than in OLETF rat. The microstructural and mechanical properties were deteriorated and decreased in OLETF rat. The results showed that bone strength is decreased in OLETF in spite of high body weight.

AB - Investigation of the bone mineral density (BMD), microstructural and mechanical properties in the Otsuka Long Evans Tokushima Fatty (OLETF) and Otsuka Long Evans Tokushima Fatty (LETO) rats were performed. The BMD and microstructural analyses were carried out using PIXI-mus and non-invasive high-resolution micro-computed tomography (micro-CT) system. The mechanical properties analyses were determined by finite element analysis based on micro-images. The BMD was significantly larger in LETO rat than in OLETF rat. The microstructural and mechanical properties were deteriorated and decreased in OLETF rat. The results showed that bone strength is decreased in OLETF in spite of high body weight.

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JO - Key Engineering Materials

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Non-invasive analysis of trabecular microstructural and biomechanical properties in obese OLETF rats

Abstract

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