Non spherical polyvinyl alcohol versus gelatin sponge particles for uterine artery embolization for symptomatic fibroids

Yun Gyu Song, Hong Jang, Keung Do Park, ManDeuk Kim, Chang Woon Kim

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: To compare clinical and magnetic resonance imaging (MRI) outcomes after uterine artery embolization (UAE) with non spherical polyvinyl alcohol (nPVA) versus gelatin sponge particles. Material and methods: During ten months, from Jan 2011 to Oct 2011, 60 patients underwent UAE in a standardized manner. nPVA (n = 30) or gelatin sponge particles (n = 30) were used in all patients. Pelvic MRI and clinical symptoms were reviewed before and after the procedure. Changes in tumor, uterine volume and infarction rate of dominant tumor were assessed using MRI. Result: At three months after embolization, the outcome data were collected. The improvement of the mean bleeding score was more pronounced with gelatin sponge particles than with nPVA particles (p = 0.035). The mean volume reduction rate and infarction rate of dominant fibroid were 47.9 ± 20.8%, 97.7 ± 5.2% and 60.2 ± 18.1, 96 ± 7.0% after UAE with nPVA compared to gelatin sponge particles, respectively. Conclusion: This study showed the superiority of gelatin sponge particles over nPVA in terms of improvement of mean bleeding score and volume reduction rate of dominant fibroid at three months follow-up after UAE, although the infarction rate of dominant fibroid was similar across groups at three months.

Original languageEnglish
Pages (from-to)364-371
Number of pages8
JournalMinimally Invasive Therapy and Allied Technologies
Volume22
Issue number6
DOIs
Publication statusPublished - 2013 Dec 1

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Uterine Artery Embolization
Polyvinyl Alcohol
Leiomyoma
Porifera
Gelatin
Infarction
Magnetic Resonance Imaging
Hemorrhage
Tumor Burden
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

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abstract = "Purpose: To compare clinical and magnetic resonance imaging (MRI) outcomes after uterine artery embolization (UAE) with non spherical polyvinyl alcohol (nPVA) versus gelatin sponge particles. Material and methods: During ten months, from Jan 2011 to Oct 2011, 60 patients underwent UAE in a standardized manner. nPVA (n = 30) or gelatin sponge particles (n = 30) were used in all patients. Pelvic MRI and clinical symptoms were reviewed before and after the procedure. Changes in tumor, uterine volume and infarction rate of dominant tumor were assessed using MRI. Result: At three months after embolization, the outcome data were collected. The improvement of the mean bleeding score was more pronounced with gelatin sponge particles than with nPVA particles (p = 0.035). The mean volume reduction rate and infarction rate of dominant fibroid were 47.9 ± 20.8{\%}, 97.7 ± 5.2{\%} and 60.2 ± 18.1, 96 ± 7.0{\%} after UAE with nPVA compared to gelatin sponge particles, respectively. Conclusion: This study showed the superiority of gelatin sponge particles over nPVA in terms of improvement of mean bleeding score and volume reduction rate of dominant fibroid at three months follow-up after UAE, although the infarction rate of dominant fibroid was similar across groups at three months.",
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Non spherical polyvinyl alcohol versus gelatin sponge particles for uterine artery embolization for symptomatic fibroids. / Song, Yun Gyu; Jang, Hong; Park, Keung Do; Kim, ManDeuk; Kim, Chang Woon.

In: Minimally Invasive Therapy and Allied Technologies, Vol. 22, No. 6, 01.12.2013, p. 364-371.

Research output: Contribution to journalArticle

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