Non-tuberculous mycobacterial lung disease presenting as a solitary pulmonary nodule

Song Yee Kim, Kyung Jong Lee, Sang Hoon Lee, Sang Kook Lee, Byung Hoon Park, Ji Ye Jung, Ji Young Son, Yoe Wun Yoon, Hyo Sup Shim, Young Ae Kang, Moo Suk Park, Young Sam Kim, Joon Chang, Se Kyu Kim, Jin Wook Moon

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Abstract

We report a case of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule (SPN). A 35-year-old male was admitted due to a SPN in the right upper lobe which was detected on the chest radiography being examed due to recurrent cough for 1 year. The computed tomography (CT) revealed a spiculated nodule containing air-bronchogram, which was suspicious of malignancy. We performed transbronchial biopsy and the pathology showed granulomatous inflammation with caseous necrosis. Under the presumptive diagnosis of pulmonary tuberculosis, we started anti-tuberculous medication including isoniazid, rifampin, ethambutol, and pyrazinamide. In one month, however, the sputum culture was positive for Mycobacterium intracellulare. The follow-up chest CT showed slight aggravation of the previous lesions. Under the final diagnosis of Mycobacterium intracellulare pulmonary infection presenting as a solitary pulmonary nodule, we changed the regimen to rifampin, ethambutol, and clarithromycin. The follow-up chest CT after the completion of treatment, revealed resolution of the previous lesions. Copyright

Original languageEnglish
Pages (from-to)43-47
Number of pages5
JournalTuberculosis and Respiratory Diseases
Volume69
Issue number1
DOIs
Publication statusPublished - 2010 Jul 31

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All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

Cite this

Kim, S. Y., Lee, K. J., Lee, S. H., Lee, S. K., Park, B. H., Jung, J. Y., Son, J. Y., Yoon, Y. W., Shim, H. S., Kang, Y. A., Park, M. S., Kim, Y. S., Chang, J., Kim, S. K., & Moon, J. W. (2010). Non-tuberculous mycobacterial lung disease presenting as a solitary pulmonary nodule. Tuberculosis and Respiratory Diseases, 69(1), 43-47. https://doi.org/10.4046/trd.2010.69.1.43