Noncompliance with the World Health Organization-Multidrug Therapy Among Leprosy Patients in Cebu, Philippines: Its Causes and Implications on the Leprosy Control Program

Elsie R. Honrado, Veronica Tallo, Angelita C. Balis, Gertrude P. Chan, Sang Nae Cho

Research output: Contribution to journalReview article

16 Citations (Scopus)

Abstract

The success of current World Health Organization (WHO) key strategy for leprosy elimination (ie, multidrug therapy [MDT] regimen) depends largely on the efficiency of health care delivery services and patient compliance. A high rate of noncompliance with this regimen has serious implications for the leprosy control program because it can set the stage for the emergence of drug resistance, eventually resulting in treatment failure and failure of the program. A community-based descriptive study using pretested interviews conducted in 12 leprosy endemic areas in Cebu, Philippines, showed that the noncompliance rate with the WHO-MDT regimen among 233 study subjects was 30%. The causes of noncompliance are drug-related, health care provider-triggered, or patient-inducted, or some combination of these. Recommendations on strategic interventions to obviate the cause for noncompliance are presented.

Original languageEnglish
Pages (from-to)221-229
Number of pages9
JournalDermatologic Clinics
Volume26
Issue number2
DOIs
Publication statusPublished - 2008 Apr 1

Fingerprint

Philippines
Leprosy
Patient Compliance
Treatment Failure
Drug Resistance
Health Personnel
Therapeutics
Interviews
Delivery of Health Care
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

@article{6163f949b3074698a420c3710f5c9582,
title = "Noncompliance with the World Health Organization-Multidrug Therapy Among Leprosy Patients in Cebu, Philippines: Its Causes and Implications on the Leprosy Control Program",
abstract = "The success of current World Health Organization (WHO) key strategy for leprosy elimination (ie, multidrug therapy [MDT] regimen) depends largely on the efficiency of health care delivery services and patient compliance. A high rate of noncompliance with this regimen has serious implications for the leprosy control program because it can set the stage for the emergence of drug resistance, eventually resulting in treatment failure and failure of the program. A community-based descriptive study using pretested interviews conducted in 12 leprosy endemic areas in Cebu, Philippines, showed that the noncompliance rate with the WHO-MDT regimen among 233 study subjects was 30{\%}. The causes of noncompliance are drug-related, health care provider-triggered, or patient-inducted, or some combination of these. Recommendations on strategic interventions to obviate the cause for noncompliance are presented.",
author = "Honrado, {Elsie R.} and Veronica Tallo and Balis, {Angelita C.} and Chan, {Gertrude P.} and Cho, {Sang Nae}",
year = "2008",
month = "4",
day = "1",
doi = "10.1016/j.det.2007.11.007",
language = "English",
volume = "26",
pages = "221--229",
journal = "Dermatologic Clinics",
issn = "0733-8635",
publisher = "W.B. Saunders Ltd",
number = "2",

}

Noncompliance with the World Health Organization-Multidrug Therapy Among Leprosy Patients in Cebu, Philippines : Its Causes and Implications on the Leprosy Control Program. / Honrado, Elsie R.; Tallo, Veronica; Balis, Angelita C.; Chan, Gertrude P.; Cho, Sang Nae.

In: Dermatologic Clinics, Vol. 26, No. 2, 01.04.2008, p. 221-229.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Noncompliance with the World Health Organization-Multidrug Therapy Among Leprosy Patients in Cebu, Philippines

T2 - Its Causes and Implications on the Leprosy Control Program

AU - Honrado, Elsie R.

AU - Tallo, Veronica

AU - Balis, Angelita C.

AU - Chan, Gertrude P.

AU - Cho, Sang Nae

PY - 2008/4/1

Y1 - 2008/4/1

N2 - The success of current World Health Organization (WHO) key strategy for leprosy elimination (ie, multidrug therapy [MDT] regimen) depends largely on the efficiency of health care delivery services and patient compliance. A high rate of noncompliance with this regimen has serious implications for the leprosy control program because it can set the stage for the emergence of drug resistance, eventually resulting in treatment failure and failure of the program. A community-based descriptive study using pretested interviews conducted in 12 leprosy endemic areas in Cebu, Philippines, showed that the noncompliance rate with the WHO-MDT regimen among 233 study subjects was 30%. The causes of noncompliance are drug-related, health care provider-triggered, or patient-inducted, or some combination of these. Recommendations on strategic interventions to obviate the cause for noncompliance are presented.

AB - The success of current World Health Organization (WHO) key strategy for leprosy elimination (ie, multidrug therapy [MDT] regimen) depends largely on the efficiency of health care delivery services and patient compliance. A high rate of noncompliance with this regimen has serious implications for the leprosy control program because it can set the stage for the emergence of drug resistance, eventually resulting in treatment failure and failure of the program. A community-based descriptive study using pretested interviews conducted in 12 leprosy endemic areas in Cebu, Philippines, showed that the noncompliance rate with the WHO-MDT regimen among 233 study subjects was 30%. The causes of noncompliance are drug-related, health care provider-triggered, or patient-inducted, or some combination of these. Recommendations on strategic interventions to obviate the cause for noncompliance are presented.

UR - http://www.scopus.com/inward/record.url?scp=40849098794&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=40849098794&partnerID=8YFLogxK

U2 - 10.1016/j.det.2007.11.007

DO - 10.1016/j.det.2007.11.007

M3 - Review article

C2 - 18346553

AN - SCOPUS:40849098794

VL - 26

SP - 221

EP - 229

JO - Dermatologic Clinics

JF - Dermatologic Clinics

SN - 0733-8635

IS - 2

ER -