Nondestructive, colorimetric monitoring of amines and thiols on a solid support

Seh Jin Yang, Xi Zhe Tian, Injae Shin

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A new, nondestructive, highly sensitive method for colorimetric monitoring of primary amines, secondary amines, and thiols on a solid support was developed. The resin used in this method is simply regenerated for the repetition of the reaction or an ensuing reaction. By using this new method, several peptides containing secondary amide linkages and C-terminal hydrazide groups were prepared in high purities and yields.

Original languageEnglish
Pages (from-to)3438-3441
Number of pages4
JournalOrganic Letters
Volume11
Issue number15
DOIs
Publication statusPublished - 2009 Aug 6

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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