Nontuberculous mycobacterial lung disease caused by mycobacterium simiae: The first reported case in South Korea

Suk Hyeon Jeong, Su Young Kim, Hyun Lee, Jun Soo Ham, Keum Bit Hwang, Subin Hwang, Sun Hye Shin, Myung Jin Chung, Seung Heon Lee, Sung Jae Shin, Won Jung Koh

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae. The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65, rpoB, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ethambutol, and rifampin. To the best of our knowledge, this is the first confirmed case of a lung disease caused by M. simiae in South Korea.

Original languageEnglish
Pages (from-to)432-435
Number of pages4
JournalTuberculosis and Respiratory Diseases
Volume78
Issue number4
DOIs
Publication statusPublished - 2015 Oct 1

Bibliographical note

Funding Information:
This work was supported by a grant of the Korean Health Technology R&D Project, Ministry for Health & Welfare, Republic of Korea (A120647) and by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2013R1A1A2060552).

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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