Normal ambulatory 24-hour esophageal pH values in Koreans-A multicenter study-

Gwang Ha Kim, Kyu Chan Huh, Yong Chan Lee, Kwang Jae Lee, Suck Chei Choi, Ki Nam Shim, Jeong Hwan Kim, In Seok Lee, Hang Lak Lee, Hwoon Yong Jung, Hyo Jin Park

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Ambulatory 24-hr esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease. The aim of this study was to establish normal values for gastroesophageal acid exposure in healthy Koreans. Fifty healthy volunteers (24 males and 26 females; mean age, 45 yr) without reflux symptoms and without reflux esophagitis or hiatal hernia on upper endoscopy underwent ambulatory 24-hr esophageal pH monitoring after esophageal manometry. The 95th percentiles for the reflux parameters were: the percent total time pH <4, 3.7%; the percent upright time pH <4, 5.7%; the percent supine time pH <4, 1.0%; the number of reflux episodes with pH <4, 76.5; the number of reflux episodes with pH <4 for >5 min, 1.5; the duration of the longest episode, 12.5 min; and the composite score, 14.2. Age and gender were not associated with any of the pH parameters. In conclusion, physiological gastroesophageal reflux occurs in healthy Koreans. These normal esophageal pH values will provide reference data for clinical and research studies in Korea.

Original languageEnglish
Pages (from-to)954-958
Number of pages5
JournalJournal of Korean medical science
Volume23
Issue number6
DOIs
Publication statusPublished - 2008 Dec 1

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Esophageal pH Monitoring
Multicenter Studies
Gastroesophageal Reflux
Peptic Esophagitis
Hiatal Hernia
Manometry
Korea
Endoscopy
Healthy Volunteers
Reference Values
Acids
Research
Clinical Studies

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kim, Gwang Ha ; Huh, Kyu Chan ; Lee, Yong Chan ; Lee, Kwang Jae ; Choi, Suck Chei ; Shim, Ki Nam ; Kim, Jeong Hwan ; Lee, In Seok ; Lee, Hang Lak ; Jung, Hwoon Yong ; Park, Hyo Jin. / Normal ambulatory 24-hour esophageal pH values in Koreans-A multicenter study-. In: Journal of Korean medical science. 2008 ; Vol. 23, No. 6. pp. 954-958.
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Kim, GH, Huh, KC, Lee, YC, Lee, KJ, Choi, SC, Shim, KN, Kim, JH, Lee, IS, Lee, HL, Jung, HY & Park, HJ 2008, 'Normal ambulatory 24-hour esophageal pH values in Koreans-A multicenter study-', Journal of Korean medical science, vol. 23, no. 6, pp. 954-958. https://doi.org/10.3346/jkms.2008.23.6.954

Normal ambulatory 24-hour esophageal pH values in Koreans-A multicenter study-. / Kim, Gwang Ha; Huh, Kyu Chan; Lee, Yong Chan; Lee, Kwang Jae; Choi, Suck Chei; Shim, Ki Nam; Kim, Jeong Hwan; Lee, In Seok; Lee, Hang Lak; Jung, Hwoon Yong; Park, Hyo Jin.

In: Journal of Korean medical science, Vol. 23, No. 6, 01.12.2008, p. 954-958.

Research output: Contribution to journalArticle

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AU - Kim, Gwang Ha

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AU - Lee, Yong Chan

AU - Lee, Kwang Jae

AU - Choi, Suck Chei

AU - Shim, Ki Nam

AU - Kim, Jeong Hwan

AU - Lee, In Seok

AU - Lee, Hang Lak

AU - Jung, Hwoon Yong

AU - Park, Hyo Jin

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Y1 - 2008/12/1

N2 - Ambulatory 24-hr esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease. The aim of this study was to establish normal values for gastroesophageal acid exposure in healthy Koreans. Fifty healthy volunteers (24 males and 26 females; mean age, 45 yr) without reflux symptoms and without reflux esophagitis or hiatal hernia on upper endoscopy underwent ambulatory 24-hr esophageal pH monitoring after esophageal manometry. The 95th percentiles for the reflux parameters were: the percent total time pH <4, 3.7%; the percent upright time pH <4, 5.7%; the percent supine time pH <4, 1.0%; the number of reflux episodes with pH <4, 76.5; the number of reflux episodes with pH <4 for >5 min, 1.5; the duration of the longest episode, 12.5 min; and the composite score, 14.2. Age and gender were not associated with any of the pH parameters. In conclusion, physiological gastroesophageal reflux occurs in healthy Koreans. These normal esophageal pH values will provide reference data for clinical and research studies in Korea.

AB - Ambulatory 24-hr esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease. The aim of this study was to establish normal values for gastroesophageal acid exposure in healthy Koreans. Fifty healthy volunteers (24 males and 26 females; mean age, 45 yr) without reflux symptoms and without reflux esophagitis or hiatal hernia on upper endoscopy underwent ambulatory 24-hr esophageal pH monitoring after esophageal manometry. The 95th percentiles for the reflux parameters were: the percent total time pH <4, 3.7%; the percent upright time pH <4, 5.7%; the percent supine time pH <4, 1.0%; the number of reflux episodes with pH <4, 76.5; the number of reflux episodes with pH <4 for >5 min, 1.5; the duration of the longest episode, 12.5 min; and the composite score, 14.2. Age and gender were not associated with any of the pH parameters. In conclusion, physiological gastroesophageal reflux occurs in healthy Koreans. These normal esophageal pH values will provide reference data for clinical and research studies in Korea.

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