Nosocomial outbreak caused by NDM-5 and OXA-181 carbapenemase co-producing Escherichia coli

Kwangjin Ahn, Gyu Yel Hwang, Young Keun Kim, Hyo Youl Kim, Hye Ran Jeong, Jun Sung Hong, Young Uh

Research output: Contribution to journalArticle


Carbapenemase-producing Enterobacteriaceae (CPE) is an important and increasing threat to global health. From July to September 2017, 20 inpatients at a tertiary care hospital in Korea were either colonized or infected with carbapenem-resistant Escherichia coli strains. All of E. coli isolates co-produced blaNDM-5 and blaOXA-181 carbapenemase genes and shared ≥88% clonal relatedness on the basis of a cladistic calculation of the distribution of pulsed-field gel electrophoresis patterns. Rapid detection of CPE is one of the most important factors to prevent CPE dissemination because it takes long time for CPE to become negative.

Original languageEnglish
Pages (from-to)177-182
Number of pages6
JournalInfection and Chemotherapy
Issue number2
Publication statusPublished - 2019 Jan 1


All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Pharmacology (medical)

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