Novel label free detection platform with ultra-high sensitivity using magnetic beads for prostate-specific antigen (psa)

Kyeong Sik Shin, Jae Hoon Ji, Seong Chan Jun, Ji Yoon Kang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, we proposes a Bead-based Electrochemical Impedance Spectroscopy (BEIS) platform to provide ultra-high sensitivity of EIS sensor by microwell array as well as reusability by using magnetic beads, for the first time. This novel detection platform enable to detect Prostate-specific antigen (PSA) using magnetic beads by EIS method without any immobilization on the electrodes of sensors, it shows the ability to detect a few fM (<100fg/mL) of PSA, which allows simplifying the measurement procedure with ultra-high sensitivity and recyclability by only changing magnet beads.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1628-1630
Number of pages3
ISBN (Electronic)9780979806483
Publication statusPublished - 2015 Jan 1
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 2015 Oct 252015 Oct 29

Other

Other19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
CountryKorea, Republic of
CityGyeongju
Period15/10/2515/10/29

Fingerprint

Antigens
Labels
Sensors
Reusability
Electrochemical impedance spectroscopy
Magnets
Electrodes

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Shin, K. S., Ji, J. H., Jun, S. C., & Kang, J. Y. (2015). Novel label free detection platform with ultra-high sensitivity using magnetic beads for prostate-specific antigen (psa). In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1628-1630). Chemical and Biological Microsystems Society.
Shin, Kyeong Sik ; Ji, Jae Hoon ; Jun, Seong Chan ; Kang, Ji Yoon. / Novel label free detection platform with ultra-high sensitivity using magnetic beads for prostate-specific antigen (psa). MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2015. pp. 1628-1630
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abstract = "In this paper, we proposes a Bead-based Electrochemical Impedance Spectroscopy (BEIS) platform to provide ultra-high sensitivity of EIS sensor by microwell array as well as reusability by using magnetic beads, for the first time. This novel detection platform enable to detect Prostate-specific antigen (PSA) using magnetic beads by EIS method without any immobilization on the electrodes of sensors, it shows the ability to detect a few fM (<100fg/mL) of PSA, which allows simplifying the measurement procedure with ultra-high sensitivity and recyclability by only changing magnet beads.",
author = "Shin, {Kyeong Sik} and Ji, {Jae Hoon} and Jun, {Seong Chan} and Kang, {Ji Yoon}",
year = "2015",
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language = "English",
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Shin, KS, Ji, JH, Jun, SC & Kang, JY 2015, Novel label free detection platform with ultra-high sensitivity using magnetic beads for prostate-specific antigen (psa). in MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, pp. 1628-1630, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015, Gyeongju, Korea, Republic of, 15/10/25.

Novel label free detection platform with ultra-high sensitivity using magnetic beads for prostate-specific antigen (psa). / Shin, Kyeong Sik; Ji, Jae Hoon; Jun, Seong Chan; Kang, Ji Yoon.

MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2015. p. 1628-1630.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Shin KS, Ji JH, Jun SC, Kang JY. Novel label free detection platform with ultra-high sensitivity using magnetic beads for prostate-specific antigen (psa). In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2015. p. 1628-1630