Novel threadlike structures on the surfaces of mammalian abdominal organs are loose bundles of fibrous stroma with microchannels embedded with fibroblasts and inflammatory cells.

Byung Cheon Lee, Baeckkyoung Sung, Ki Hoon Eom, Eun Sung Park, Min Su Kim, Se Hoon Kim, Vyacheslav Ogay, Ki Woo Kim, Yeonhee Ryu, Yeo Sung Yoon, Kwang Sup Soh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Novel threadlike structures (NTSs) on the surfaces of mammalian abdominal organs have recently attracted interests regarding their ability to transport fluid, enable cell migration, and possibly facilitate cancer metastasis. Nevertheless, histological studies of NTSs have been sporadic and often have inconsistent interpretations of the NTS internal structure. In this article, we provide a synthetic and consistent view of the NTS internal structure: the NTS is a loose bundle of fibrous stroma that forms interstitial channels and microsinusoids infiltrated with inflammatory cells. The fibroblasts are embedded in the stroma and mostly aligned along the major axis of the NTS. The sinusoids, which are in inconsecutive cross sections, have boundaries more or less delineated by extracellular fibers, partly surrounded by endothelial-like cells, or both. We compare these morphological features to other well-known connective tissues (i.e., trabecular meshwork and lymphatic capillary) and discuss the biomechanical and biological functions of NTSs based on their structural characteristics.

Original languageEnglish
Pages (from-to)94-100
Number of pages7
JournalUnknown Journal
Volume54
Issue number2
DOIs
Publication statusPublished - 2013

Fingerprint

Trabecular Meshwork
Lymphatic Vessels
Fibroblasts
Microchannels
Connective Tissue
Cell Movement
Endothelial Cells
Tissue
Neoplasm Metastasis
Fluids
Fibers
Neoplasms

All Science Journal Classification (ASJC) codes

  • Rheumatology
  • Biochemistry
  • Orthopedics and Sports Medicine
  • Molecular Biology
  • Cell Biology

Cite this

Lee, Byung Cheon ; Sung, Baeckkyoung ; Eom, Ki Hoon ; Park, Eun Sung ; Kim, Min Su ; Kim, Se Hoon ; Ogay, Vyacheslav ; Kim, Ki Woo ; Ryu, Yeonhee ; Yoon, Yeo Sung ; Soh, Kwang Sup. / Novel threadlike structures on the surfaces of mammalian abdominal organs are loose bundles of fibrous stroma with microchannels embedded with fibroblasts and inflammatory cells. In: Unknown Journal. 2013 ; Vol. 54, No. 2. pp. 94-100.
@article{8c4ceb282fc249ad856ca2353c60a8d9,
title = "Novel threadlike structures on the surfaces of mammalian abdominal organs are loose bundles of fibrous stroma with microchannels embedded with fibroblasts and inflammatory cells.",
abstract = "Novel threadlike structures (NTSs) on the surfaces of mammalian abdominal organs have recently attracted interests regarding their ability to transport fluid, enable cell migration, and possibly facilitate cancer metastasis. Nevertheless, histological studies of NTSs have been sporadic and often have inconsistent interpretations of the NTS internal structure. In this article, we provide a synthetic and consistent view of the NTS internal structure: the NTS is a loose bundle of fibrous stroma that forms interstitial channels and microsinusoids infiltrated with inflammatory cells. The fibroblasts are embedded in the stroma and mostly aligned along the major axis of the NTS. The sinusoids, which are in inconsecutive cross sections, have boundaries more or less delineated by extracellular fibers, partly surrounded by endothelial-like cells, or both. We compare these morphological features to other well-known connective tissues (i.e., trabecular meshwork and lymphatic capillary) and discuss the biomechanical and biological functions of NTSs based on their structural characteristics.",
author = "Lee, {Byung Cheon} and Baeckkyoung Sung and Eom, {Ki Hoon} and Park, {Eun Sung} and Kim, {Min Su} and Kim, {Se Hoon} and Vyacheslav Ogay and Kim, {Ki Woo} and Yeonhee Ryu and Yoon, {Yeo Sung} and Soh, {Kwang Sup}",
year = "2013",
doi = "10.3109/03008207.2012.748757",
language = "English",
volume = "54",
pages = "94--100",
journal = "Review of Economic Dynamics",
issn = "1094-2025",
publisher = "Academic Press Inc.",
number = "2",

}

Novel threadlike structures on the surfaces of mammalian abdominal organs are loose bundles of fibrous stroma with microchannels embedded with fibroblasts and inflammatory cells. / Lee, Byung Cheon; Sung, Baeckkyoung; Eom, Ki Hoon; Park, Eun Sung; Kim, Min Su; Kim, Se Hoon; Ogay, Vyacheslav; Kim, Ki Woo; Ryu, Yeonhee; Yoon, Yeo Sung; Soh, Kwang Sup.

In: Unknown Journal, Vol. 54, No. 2, 2013, p. 94-100.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Novel threadlike structures on the surfaces of mammalian abdominal organs are loose bundles of fibrous stroma with microchannels embedded with fibroblasts and inflammatory cells.

AU - Lee, Byung Cheon

AU - Sung, Baeckkyoung

AU - Eom, Ki Hoon

AU - Park, Eun Sung

AU - Kim, Min Su

AU - Kim, Se Hoon

AU - Ogay, Vyacheslav

AU - Kim, Ki Woo

AU - Ryu, Yeonhee

AU - Yoon, Yeo Sung

AU - Soh, Kwang Sup

PY - 2013

Y1 - 2013

N2 - Novel threadlike structures (NTSs) on the surfaces of mammalian abdominal organs have recently attracted interests regarding their ability to transport fluid, enable cell migration, and possibly facilitate cancer metastasis. Nevertheless, histological studies of NTSs have been sporadic and often have inconsistent interpretations of the NTS internal structure. In this article, we provide a synthetic and consistent view of the NTS internal structure: the NTS is a loose bundle of fibrous stroma that forms interstitial channels and microsinusoids infiltrated with inflammatory cells. The fibroblasts are embedded in the stroma and mostly aligned along the major axis of the NTS. The sinusoids, which are in inconsecutive cross sections, have boundaries more or less delineated by extracellular fibers, partly surrounded by endothelial-like cells, or both. We compare these morphological features to other well-known connective tissues (i.e., trabecular meshwork and lymphatic capillary) and discuss the biomechanical and biological functions of NTSs based on their structural characteristics.

AB - Novel threadlike structures (NTSs) on the surfaces of mammalian abdominal organs have recently attracted interests regarding their ability to transport fluid, enable cell migration, and possibly facilitate cancer metastasis. Nevertheless, histological studies of NTSs have been sporadic and often have inconsistent interpretations of the NTS internal structure. In this article, we provide a synthetic and consistent view of the NTS internal structure: the NTS is a loose bundle of fibrous stroma that forms interstitial channels and microsinusoids infiltrated with inflammatory cells. The fibroblasts are embedded in the stroma and mostly aligned along the major axis of the NTS. The sinusoids, which are in inconsecutive cross sections, have boundaries more or less delineated by extracellular fibers, partly surrounded by endothelial-like cells, or both. We compare these morphological features to other well-known connective tissues (i.e., trabecular meshwork and lymphatic capillary) and discuss the biomechanical and biological functions of NTSs based on their structural characteristics.

UR - http://www.scopus.com/inward/record.url?scp=84878687829&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878687829&partnerID=8YFLogxK

U2 - 10.3109/03008207.2012.748757

DO - 10.3109/03008207.2012.748757

M3 - Article

C2 - 23186263

AN - SCOPUS:84878687829

VL - 54

SP - 94

EP - 100

JO - Review of Economic Dynamics

JF - Review of Economic Dynamics

SN - 1094-2025

IS - 2

ER -