Observation of Cell Division in a Fertilized Egg of a Zebrafish by Using a Multimodal Nonlinear Optical Microscope

Sung Ho Lee, Seung Hyun Hong, Seung Han Park, Boram Kim, Dong Hee Kim, Seung Woo Park

Research output: Contribution to journalArticle

Abstract

We have developed a high-speed and high-resolution multimodal nonlinear optical microscope, which can acquire in vivo label and label-free 3D images. Using this microscope, we could successfully observe dynamic images of the zebrafish heartbeat with 33-millisecond intervals without staining process, indicating 1.68 beats per second. In addition, we show that the label-free, high-speed, real-time images can be obtained during somatic cell divisions in the zebrafish’s embryo.

Original languageEnglish
Pages (from-to)485-489
Number of pages5
JournalJournal of the Korean Physical Society
Volume75
Issue number6
DOIs
Publication statusPublished - 2019 Sep 1

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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