Observation of proliferation and attachment of three different cell types on nano-fibrous silk film & scaffold

Hyun Sook Baek, Young Hwan Park, Ki Chang Seok, Jongchul Park, Dong Kyun Rah

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Attachment and viability of different cell types(fibrioblast, chondrocyte and osteoblast) was observed on two forms of silk (mat & Three-dimensional scaffolds). The osteoblasts behaviors cultured on silk mat were significantly higher than that found on 3-D silk fibroin scaffold (3-D SF scaffold). In the MTT assay, the cell viability of fibroblasts, chondrocyte and osteoblasts seeded on 2-D nanofiber mat was (2-D mat) significantly higher than that found on 3-D SF scaffold. Similar result could be seen from SEM observation and cell attachment study. However, alkaline phosphatase activity was significantly increased on 3-D SF scaffold than on2-D nanofiber.

Original languageEnglish
Pages (from-to)85-88
Number of pages4
JournalKey Engineering Materials
Volume342-343
Publication statusPublished - 2007 Apr 16

Fingerprint

Silk
Scaffolds
Osteoblasts
Nanofibers
Cells
Fibroins
Forms (concrete)
Phosphatases
Fibroblasts
Alkaline Phosphatase
Assays
Scanning electron microscopy

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Baek, Hyun Sook ; Park, Young Hwan ; Seok, Ki Chang ; Park, Jongchul ; Rah, Dong Kyun. / Observation of proliferation and attachment of three different cell types on nano-fibrous silk film & scaffold. In: Key Engineering Materials. 2007 ; Vol. 342-343. pp. 85-88.
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Observation of proliferation and attachment of three different cell types on nano-fibrous silk film & scaffold. / Baek, Hyun Sook; Park, Young Hwan; Seok, Ki Chang; Park, Jongchul; Rah, Dong Kyun.

In: Key Engineering Materials, Vol. 342-343, 16.04.2007, p. 85-88.

Research output: Contribution to journalArticle

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